Haas Gerda-Maria, Liepold Evelyn, Schwandt Peter
Atherosclerosis Prevention Institute, Munich-Nuremberg, 81477 Munich, Germany.
Cholesterol. 2012;2012:370850. doi: 10.1155/2012/370850. Epub 2012 Jun 19.
Purpose. We assessed the five components of the metabolic syndrome (MetS) as defined by the International Diabetes Federation (IDF) in 6040 (3158 males) youths aged 6-16 years who participated in the Präventions-Erziehungs-Programm (PEP Family Heart Study) in Nuernberg between 2000 and 2007. The purpose of this cross-sectional study was to examine associations with lifestyle habits. Results and Discussion. The prevalence of MetS was low in children (1.6%) and adolescents (2.3%). High waist circumference (WC) and low HDL-C were slightly higher in females (9.5% and 7.5%, resp.) than in males (8.8% and 5.7%, resp.). Low leisure time physical activity (LTPA) was significantly associated with low HDL-C (odds ratio [OR] 2.4; 95% CI 1.2-5.0) and inversely associated with hypertension (r = -0.146), hypertriglyceridemia (r = -0.141), and central adiposity (r = -0.258). The risk for low HDL-C (≤1.3 mmol/L) was 1.7-fold (CI 1.0-2.6) higher in youth with high (≥33%) saturated fat consumption. A low polyunsaturated/saturated fat ratio (P/S ratio) was significantly associated with fasting hyperglycemia (OR 1.4; 95% CI 1.0-1.2).
目的。我们评估了国际糖尿病联盟（IDF）定义的代谢综合征（MetS）的五个组成部分，研究对象为2000年至2007年间参与纽伦堡预防 - 教育项目（PEP家庭心脏研究）的6040名6至16岁的青少年（3158名男性）。这项横断面研究的目的是检验与生活方式习惯的关联。结果与讨论。儿童（1.6%）和青少年（2.3%）中MetS的患病率较低。女性的高腰围（WC）和低高密度脂蛋白胆固醇（HDL - C）的比例略高于男性（分别为9.5%和7.5%）（男性分别为8.8%和5.7%）。低休闲时间体力活动（LTPA）与低HDL - C显著相关（优势比[OR] 2.4；95%置信区间1.2 - 5.0），与高血压（r = -0.146）、高甘油三酯血症（r = -0.141）和中心性肥胖（r = -0.258）呈负相关。饱和脂肪摄入量高（≥33%）的青少年中，低HDL - C（≤1.3 mmol/L）的风险高1.7倍（置信区间1.0 - 2.6）。低多不饱和/饱和脂肪比例（P/S比例）与空腹血糖过高显著相关（OR 1.4；95%置信区间1.0 - 1.2）。
