Skrbić Dusan, Stojanović Goran, Povazan Djordje, Djurć Mirna, Eri Zivka
Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.
Vojnosanit Pregl. 2012 Jun;69(6):531-5.
Autofluorescence bronchoscopy (AFB) is a diagnostic procedure that is included in all diagnostic algorithms discovering precancerous lesions in the large airways.
We presented a 71-year-old patient submitted to exploration due to prolonged cough. Both noninvasive and invasive pulmonary diagnostic management was carried out. On bronchoscopy, an endobronchial mass was detected in the apical bronchus. A positive endoscopy finding indicated AFB which disclosed a fluorescence alteration of the tumor mucosa and the former bronchoscopy site. Histopathological analysis of the catheter biopsy obtained samples from the right upper lobe confirmed fibrinous purulent pneumonia in organization. The applied treatment resulted in regression of both symptoms and the lesion in the right upper lobe. Due to a positive AFB finding, the patient was regularly observed over the following three years, having had three control AFB to monitor the initial finding.
AFB may be utilized in the routine of everyday practice to assess the spread of the disease, as well as in the postsurgical and long-term follow-up of operated patients. The procedure may also be applied to enable an easier and more reliable observation of patients with suspicious endobronchial lesions, smokers with altered fluorescence of the bronchial mucosa, and chronic patients.
自体荧光支气管镜检查（AFB）是一种诊断程序，包含在所有用于发现大气道癌前病变的诊断算法中。
我们介绍了一名71岁因长期咳嗽接受检查的患者。进行了无创和有创肺部诊断管理。在支气管镜检查中，在尖段支气管发现了一个支气管内肿块。内镜检查阳性结果提示AFB，其显示肿瘤黏膜和先前支气管镜检查部位有荧光改变。对经导管活检从右上叶获取的样本进行组织病理学分析，证实为机化性纤维脓性肺炎。所应用的治疗使症状和右上叶病变消退。由于AFB检查结果阳性，在接下来的三年里对该患者进行了定期观察，进行了三次对照AFB检查以监测最初的检查结果。
AFB可用于日常临床实践中评估疾病的扩散情况，以及用于手术患者的术后和长期随访。该程序还可用于更轻松、更可靠地观察有可疑支气管内病变的患者、支气管黏膜荧光改变的吸烟者以及慢性病患者。
