Institute of Physical Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
J Chem Phys. 2012 Jul 7;137(1):015101. doi: 10.1063/1.4731646.
Vesicles composed of a two component membrane with each component characterized by different spontaneous curvature are investigated by minimization of the free energy consisting of Helfrich elastic energy and entropy of mixing. The results show that mixing and demixing of membrane components can be induced by elongating a vesicle or changing its volume, if one of the components forms a complex with macromolecules on the outer monolayer. The influence of elastic coefficients on the separation of components is also examined.
我们通过最小化由 Helfrich 弹性能量和混合熵组成的自由能来研究由具有不同自发曲率的两个组件组成的囊泡。结果表明，如果其中一个组件在外层单层上与大分子形成复合物，则通过拉长囊泡或改变其体积可以诱导膜组件的混合和分离。我们还研究了弹性系数对组件分离的影响。
