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[慢性阻塞性肺疾病严重加重合并阻塞性睡眠呼吸暂停和肥胖的治疗方法]

[Therapeutical approach in severe exacerbation of COPD associating obstructive sleep apnoea and obesity].

作者信息

Dumitrache-Rujinski Stefan, Croitoru Alina, Bogdan Miron Alexandru

机构信息

Institutul de Pneumologie Marius Nasta, Bucureşti.

出版信息

Pneumologia. 2012 Apr-Jun;61(2):117-9.

PMID:22783604
Abstract

COPD exacerbations with respiratory acidosis are difficult to manage, especially when OSA and obesity are associated. The solution is the use of noninvasive ventilation associated with oxygenotherapy in order to correct the hypercapnia, hypoxemia and respiratory acidosis and to prevent the invasive mechanical ventilation. Early respiratory rehabilitation and the use of a domiciliary ventilatory support after the acute episode could be a part of the management for these patients. We present a modality of therapeutical approach through a clinical case.

摘要

伴有呼吸性酸中毒的慢性阻塞性肺疾病急性加重期难以处理,尤其是当合并阻塞性睡眠呼吸暂停和肥胖时。解决办法是采用无创通气联合氧疗,以纠正高碳酸血症、低氧血症和呼吸性酸中毒,并预防有创机械通气。早期呼吸康复以及在急性发作后使用家庭通气支持可能是这些患者治疗的一部分。我们通过一个临床病例展示一种治疗方法。

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[Therapeutical approach in severe exacerbation of COPD associating obstructive sleep apnoea and obesity].[慢性阻塞性肺疾病严重加重合并阻塞性睡眠呼吸暂停和肥胖的治疗方法]
Pneumologia. 2012 Apr-Jun;61(2):117-9.
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[Non-invasive positive pressure ventilation in stable COPD: has it any role?].[无创正压通气在稳定期慢性阻塞性肺疾病中的作用:它有任何作用吗?]
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The overlap syndrome: chronic obstructive pulmonary disease and obstructive sleep apnea.重叠综合征:慢性阻塞性肺疾病与阻塞性睡眠呼吸暂停
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The impact of long-term conventional treatment for overlap syndrome (obstructive sleep apnea and chronic obstructive pulmonary disease) on concurrent erectile dysfunction.长期传统治疗重叠综合征(阻塞性睡眠呼吸暂停和慢性阻塞性肺疾病)对并发勃起功能障碍的影响。
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引用本文的文献

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Efficacy of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease and obstructive sleep apnea; a randomized controlled trial.肺康复对慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停患者的疗效:一项随机对照试验。
J Rehabil Med. 2024 Sep 24;56:jrm23757. doi: 10.2340/jrm.v56.23757.
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The role of overnight pulse-oximetry in recognition of obstructive sleep apnea syndrome in morbidly obese and non obese patients.夜间脉搏血氧饱和度监测在识别病态肥胖和非肥胖患者阻塞性睡眠呼吸暂停综合征中的作用。
Maedica (Bucur). 2013 Sep;8(3):237-42.