Dumitrache-Rujinski Stefan, Calcaianu George, Zaharia Dragos, Toma Claudia Lucia, Bogdan Miron
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; "Marius Nasta" Institute of Pneumology, Bucharest, Romania.
"Marius Nasta" Institute of Pneumology, Bucharest, Romania.
Maedica (Bucur). 2013 Sep;8(3):237-42.
We prospectively evaluated 199 individuals with high pre-test clinical suspicion of OSAS. Of these, 123 patients were morbidly obese (Group A) and 76 were non-obese (Group B). We performed six channel cardio-respiratory polygraphy and assessed the correlation between the Desaturation Index (DI) and the Apnea Hypopnea Index (AHI) for both groups.
In group A: 116 patients (94.3%) were diagnosed with OSAS (AHI>5/hour); mean age: 59.4±10.9 years; mean BMI: 44.8±4.9 kg/m(2). The mean DI was 47.2±27.6/hour and the mean AHI: 46.5±27.6/hour. Mean average SaO2 was 88.5±6.3 %. In group B, 65 patients (85.52%) were diagnosed with SAS; mean age: 51.2 ± 12.7 years; mean BMI: 27.24±2.2 kg/m(2).The mean DI was 23.12 ± 18.35/hour and the mean AHI: 28.8 ± 18.5/hour. Mean average SaO2 was 93.7±2.07 %.A significant positive correlation (correlation index rA = 0.863 and rB= 0.877) was found between DI and AHI in both groups (p<0.001).
Assessment of the Desaturation Index by nocturnal pulse-oximetry maintains its utility as a screening method for OSAS in both obese and non-obese patients with high clinical pre-test suspicion, despite the fact that the basal nocturnal saturation was found to be lower in group A.
我们前瞻性地评估了199例临床预测试高度怀疑患有阻塞性睡眠呼吸暂停低通气综合征(OSAS)的个体。其中,123例患者为病态肥胖(A组),76例为非肥胖患者(B组)。我们进行了六通道心肺多导睡眠监测,并评估了两组的血氧饱和度下降指数(DI)和呼吸暂停低通气指数(AHI)之间的相关性。
A组:116例患者(94.3%)被诊断为OSAS(AHI>5次/小时);平均年龄:59.4±10.9岁;平均体重指数(BMI):44.8±4.9kg/m²。平均DI为47.2±27.6次/小时,平均AHI为46.5±27.6次/小时。平均夜间血氧饱和度(SaO₂)为88.5±6.3%。B组中,65例患者(85.52%)被诊断为睡眠呼吸暂停综合征(SAS);平均年龄:51.2±12.7岁;平均BMI:27.24±2.2kg/m²。平均DI为23.12±18.35次/小时,平均AHI为28.8±18.5次/小时。平均夜间SaO₂为93.7±2.07%。两组的DI和AHI之间均发现显著正相关(相关指数rA = 0.863,rB = 0.877)(p<0.001)。
尽管A组夜间基础饱和度较低,但通过夜间脉搏血氧饱和度测定评估血氧饱和度下降指数,对于临床预测试高度怀疑的肥胖和非肥胖患者,仍可作为OSAS的筛查方法。