Determination of haloperidol and hydroxy haloperidol in human plasma by high performance liquid chromatography.
作者信息
Pommery J, Foulon O, Morineau G, Lhermitte M, Levron J C, Erb F
机构信息
Laboratoire de Toxicologie, Faculté de Pharmacie, Laguesse, Lille.
出版信息
Ann Biol Clin (Paris). 1990;48(7):455-8.
PMID:2278409
Abstract
A method has been developed for the separation and measurement of haloperidol and hydroxy haloperidol in human plasma through high performance liquid chromatography. The method uses chlorohaloperidol as an internal standard and provides a limit of detection of about 0.7 nmol/l for haloperidol and 0.67 nmol/l for hydroxy haloperidol. HPLC and RIA radioimmunoassay methods are compared.
摘要
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