Franks Stephen
Institute of Reproductive & Developmental Biology, Imperial College London, London, UK.
J Fam Plann Reprod Health Care. 2012 Jul;38(3):182-6. doi: 10.1136/jfprhc-2011-100175.
Excess male-pattern body hair in women is a very common and psychologically damaging condition. Although its cause is usually a chronic and benign disorder (most commonly polycystic ovary syndrome) it may rarely be an indication of a more serious endocrine disease such as Cushing syndrome or an androgen-secreting tumour. Investigations do not usually need to be extensive, but effective management is important, irrespective of cause, for what can be a debilitating symptom. Specific treatment of any underlying disease is important but in most cases treatment is empirical; it may simply involve physical hair removal, ideally by electrolysis or laser treatment. However, endocrine therapy to suppress androgen production and/or action is desirable in many, if not most, cases.
女性出现男性化的身体毛发过多是一种非常常见且对心理有损害的状况。尽管其病因通常是一种慢性良性疾病(最常见的是多囊卵巢综合征),但它很少可能是更严重的内分泌疾病的迹象,如库欣综合征或分泌雄激素的肿瘤。通常不需要进行广泛的检查,但无论病因如何,对于这种可能使人衰弱的症状,有效的管理很重要。对任何潜在疾病进行特异性治疗很重要,但在大多数情况下治疗是经验性的;可能仅仅涉及去除身体毛发,理想的方法是电解或激光治疗。然而,在许多(即便不是大多数)情况下,抑制雄激素产生和/或作用的内分泌治疗是可取的。