Yalta Tulin, Taştekin Ebru, Puyan Fulya Öz, Usta Ufuk, Azatçam Meltem, Altaner Semsi
Department of Pathology, Trakya University, Edirne, Turkey.
J Cytol. 2012 Apr;29(2):142-3. doi: 10.4103/0970-9371.97161.
Cervicovaginal smear screening is well known to reduce morbidity and mortality rates of invasive cervical carcinoma. Herein, we report a case of 56-year-old woman whose cervicovaginal smear was found to consist of malignant cells characterized by high nuclear/cytoplasmic ratio, scant rim of cytoplasm, coarsely granular nuclear chromatin and irregular nuclear membrane that were all reminiscent of a malignant lymphoma. Histopathological examination of the hysterectomy and unilateral adnexectomy specimen confirmed the presence of a diffuse large B-cell non Hodgkin's lymphoma involving the cervix, endometrium, myometrium, serosa and the right ovary.
宫颈阴道涂片筛查可降低浸润性宫颈癌的发病率和死亡率，这是众所周知的。在此，我们报告一例56岁女性病例，其宫颈阴道涂片发现有恶性细胞，这些细胞具有高核质比、少量细胞质边缘、粗糙颗粒状核染色质和不规则核膜等特征，这些都让人联想到恶性淋巴瘤。子宫切除及单侧附件切除标本的组织病理学检查证实存在弥漫性大B细胞非霍奇金淋巴瘤，累及宫颈、子宫内膜、肌层、浆膜和右侧卵巢。
