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非霍奇金淋巴瘤:宫颈阴道细胞学检查中罕见的诊断结果。

Non-Hodgkin's lymphoma: A rare diagnosis on cervicovaginal cytology.

作者信息

Yalta Tulin, Taştekin Ebru, Puyan Fulya Öz, Usta Ufuk, Azatçam Meltem, Altaner Semsi

机构信息

Department of Pathology, Trakya University, Edirne, Turkey.

出版信息

J Cytol. 2012 Apr;29(2):142-3. doi: 10.4103/0970-9371.97161.

Abstract

Cervicovaginal smear screening is well known to reduce morbidity and mortality rates of invasive cervical carcinoma. Herein, we report a case of 56-year-old woman whose cervicovaginal smear was found to consist of malignant cells characterized by high nuclear/cytoplasmic ratio, scant rim of cytoplasm, coarsely granular nuclear chromatin and irregular nuclear membrane that were all reminiscent of a malignant lymphoma. Histopathological examination of the hysterectomy and unilateral adnexectomy specimen confirmed the presence of a diffuse large B-cell non Hodgkin's lymphoma involving the cervix, endometrium, myometrium, serosa and the right ovary.

摘要

宫颈阴道涂片筛查可降低浸润性宫颈癌的发病率和死亡率,这是众所周知的。在此,我们报告一例56岁女性病例,其宫颈阴道涂片发现有恶性细胞,这些细胞具有高核质比、少量细胞质边缘、粗糙颗粒状核染色质和不规则核膜等特征,这些都让人联想到恶性淋巴瘤。子宫切除及单侧附件切除标本的组织病理学检查证实存在弥漫性大B细胞非霍奇金淋巴瘤,累及宫颈、子宫内膜、肌层、浆膜和右侧卵巢。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301d/3391799/fd1f92680bc2/JCytol-29-142-g001.jpg

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