García Reinoso C, Gómez Rubio M, Sáez-Royela F, Melero Calleja E
Universidad Autónoma, Clinica de La Concepción Fundación Jiménez Díaz, Madrid.
Rev Esp Enferm Dig. 1990 Sep;78(3):131-4.
Nine cases of Fournier's gangrene diagnosed between 1982 and 1989 are reported. All were males with a mean age of 76 (47-82 years). Seven had a history of alcoholism and one had non insulin-dependent diabetes. Six patients also had an anal fistula which may have been the starting point of the infection. The causal agents were two anaerobes (Clostridium perfringens and Bacteroides fragilis) two gram-negatives (Morganella morgagni and Pseudomonas aeruginosa) and one, an unidentified gram-positive. In three patients a mixed intestinal flora was isolated and in another no germs were found. All were treated with broad-spectrum antibiotics and surgery. Seven patients survived and two died.
报告了1982年至1989年间诊断出的9例福尼尔坏疽病例。所有患者均为男性，平均年龄76岁（47 - 82岁）。7例有酗酒史，1例患有非胰岛素依赖型糖尿病。6例患者还患有肛瘘，这可能是感染的起始点。致病病原体为两种厌氧菌（产气荚膜梭菌和脆弱拟杆菌）、两种革兰氏阴性菌（摩氏摩根菌和铜绿假单胞菌）以及一种未鉴定的革兰氏阳性菌。3例患者分离出混合肠道菌群，另1例未发现细菌。所有患者均接受了广谱抗生素治疗和手术。7例患者存活，2例死亡。
