Porojan M, Poantă Laura, Dumitraşcu D L
"Iuliu Haţieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Rom J Intern Med. 2012 Jan-Mar;50(1):27-31.
The number of people with diabetes mellitus (DM) is increasing. For chronic illnesses such as DM, where there is no cure, it is important to establish that therapy really makes people feel better. The purpose of the study was to analyze the quality of life in a group of diabetic patients without major complications.
The study group consisted of 50 patients, males and females, aged 60 (+/- 6), diagnosed with type 2 DM and followed up at an outpatient clinic. The Romanian version of the SF-36 questionnaire was used as a health survey tool to measure the quality of life (QOL) of patients in the study.
Validity (coefficient alpha Cronbach) was > 0.7 for all scales except social functioning. QOL scores for study group were significantly lower compared with general population. Examining the effects of insulin use and QOL, there are no significant differences between patients following insulin therapy and patients with other therapeutic protocols. Role limitations due to emotional problems correlate with disease duration. Statistical analysis demonstrates a significant correlation between energy/fatigue scores and HbA1c. There are no other statistically significant correlations between SF-36 scores and other variables analyzed.
Patients with DM have statistically significant impairment of all aspects of QOL, not simply physical functioning. DM put a substantial burden on affected individuals by influencing physical, psychological and social aspects of QOL. The progressive nature of type 2 DM and the real risk for developing chronic complications certifies that insulin use will be a reality for most diabetic patients, but its use did not seem to have a negative impact upon QOL. Glycemic control becomes an important measurement for preventing long-terms complications and provides a better QOL to diabetic patient. This end-point should be a much more important target for healthcare interventions.
糖尿病患者的数量正在增加。对于糖尿病这类无法治愈的慢性疾病，确定治疗是否真的能让患者感觉更好很重要。本研究的目的是分析一组无重大并发症的糖尿病患者的生活质量。
研究组由50名年龄在60岁（±6岁）的男性和女性患者组成，他们被诊断为2型糖尿病，并在门诊接受随访。使用罗马尼亚语版的SF - 36问卷作为健康调查工具，以测量研究中患者的生活质量（QOL）。
除社会功能外，所有量表的效度（Cronbachα系数）均>0.7。研究组的生活质量得分与普通人群相比显著更低。检查胰岛素使用与生活质量的影响，接受胰岛素治疗的患者与采用其他治疗方案的患者之间没有显著差异。因情感问题导致的角色限制与疾病持续时间相关。统计分析表明，精力/疲劳得分与糖化血红蛋白（HbA1c）之间存在显著相关性。SF - 36得分与其他分析变量之间没有其他统计学上的显著相关性。
糖尿病患者在生活质量的各个方面均存在统计学上的显著损害，而不仅仅是身体功能方面。糖尿病通过影响生活质量的身体、心理和社会方面，给受影响的个体带来了沉重负担。2型糖尿病的渐进性以及发生慢性并发症的实际风险证明，胰岛素的使用对大多数糖尿病患者来说将成为现实，但它的使用似乎对生活质量没有负面影响。血糖控制成为预防长期并发症的重要指标，并为糖尿病患者提供更好的生活质量。这一终点应该成为医疗保健干预更为重要的目标。
