Stuppia L, Palka G, Fioritoni G, Calabrese G, Guanciali Franchi P, D'Arcangelo L, Torlontano G
Institute of Biology and Genetics, University of Chieti, Italy.
Genes Chromosomes Cancer. 1990 Mar;1(4):310-1. doi: 10.1002/gcc.2870010408.
A patient with acute non-lymphoblastic leukemia, FAB type M2, showed a complex karyotype involving chromosomes 1 and 11. The breakpoints could not be exactly identified by GTG and QFQ banding. A subsequent analysis with Alul and HaeIII restriction enzyme staining allowed the detection of a translocation of the heterochromatic region of chromosome 1 to 11q21.
一名急性非淋巴细胞白血病（FAB 分型为 M2 型）患者，其核型复杂，涉及 1 号和 11 号染色体。通过 GTG 和 QFQ 显带技术无法准确确定断点位置。随后采用 Alul 和 HaeIII 限制性内切酶染色分析，检测到 1 号染色体异染色质区易位至 11q21。
