Jani Sait S N, Dal Cin P, Sandberg A A
Cancer Genet Cytogenet. 1986 Aug;22(4):367-8. doi: 10.1016/0165-4608(86)90031-2.
Changes affecting the Y chromosome in neoplasia have been documented. However, this usually occurs as a loss of the Y chromosome in the affected cells accompanied by or preceding other karyotypic changes. Involvement of the Y chromosome in a translocation is extremely rare, there being only 14 cases reported in the literature. Presented here is a case of t(Y;18) in acute myeloblastic leukemia type M2 (FAB).
