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低温大鼠动脉的介电特性。

Dielectric properties of hypothermic rat artery.

机构信息

Department of Bionics and Bioimpedance, University of Medical Sciences, Poznań, Poland.

出版信息

Colloids Surf B Biointerfaces. 2013 Jan 1;101:1-5. doi: 10.1016/j.colsurfb.2012.06.003. Epub 2012 Jun 15.

DOI:10.1016/j.colsurfb.2012.06.003
PMID:22789782
Abstract

The temperature and frequency dependencies of the dielectric parameters for the rat artery are used to analyse effects of hypothermia on this tissue. Measurements were performed over the frequency range 500 Hz to 100 kHz and at temperatures from 19 to 60°C. The artery samples contained about 12% water by mass at room temperature at a relative humidity of 70%. The frequency dependencies of the loss tangent for the control, mild hypothermic and moderate hypothermic artery exhibit two peaks at 2 kHz and 35 kHz in the α-dispersion region. The results were discussed in terms of the distribution of relaxation frequencies and the activation energy for the conduction and polarization mechanisms particularly in the elastin-water and collagen-water systems. The knowledge about dielectric behavior of the hypothermic rat artery in vitro is important due to clinical application of local and systemic hypothermia.

摘要

利用大鼠动脉的介电参数的温度和频率依赖性来分析低温对该组织的影响。测量在频率范围为 500 Hz 至 100 kHz 以及温度范围为 19°C 至 60°C 下进行。动脉样本在室温下含有约 12%的水,相对湿度为 70%。在 α 弥散区,控制、轻度低温和中度低温动脉的损耗正切的频率依赖性在 2 kHz 和 35 kHz 处呈现两个峰值。结果根据弛豫频率分布和传导及极化机制的活化能进行了讨论,特别是在弹性蛋白-水和胶原蛋白-水系统中。由于局部和全身低温的临床应用,了解体外低温大鼠动脉的介电行为非常重要。

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