Department of Bionics and Bioimpedance, Poznań University of Medical Sciences, Poznań, Poland.
Colloids Surf B Biointerfaces. 2012 Mar 1;91:266-8. doi: 10.1016/j.colsurfb.2011.11.025. Epub 2011 Nov 20.
In the course of the study, we carried out a dielectric examination to determine the effect of diabetes mellitus on the rat corneal function. Measurements were performed over the frequency range of 500 Hz-100 kHz in air and at the temperatures from 25 to 150°C. The frequency dependencies of the loss tangent for the healthy and the diabetic cornea exhibit two peaks at 2 kHz and 16 kHz in the α-dispersion region. The amplitude of these both peaks is smaller for the diabetic cornea than that for the healthy one. The temperature dependencies of the loss tangent for the healthy and the diabetic cornea reveal β-relaxation in the range of 30-70°C and 50-90°C, respectively. The present study exhibits that the dielectric spectroscopy is useful in detection of the effect of diabetes mellitus on the corneal molecular behavior.
在研究过程中，我们进行了介电测试，以确定糖尿病对大鼠角膜功能的影响。测量是在空气和 25 至 150°C 的温度范围内在 500 Hz-100 kHz 的频率范围内进行的。健康和糖尿病角膜的损耗正切的频率依赖性在α分散区域在 2 kHz 和 16 kHz 处显示出两个峰值。对于糖尿病角膜，这两个峰的幅度均小于健康角膜的幅度。健康和糖尿病角膜的损耗正切的温度依赖性分别在 30-70°C 和 50-90°C 的范围内显示出β松弛。本研究表明，介电光谱法可用于检测糖尿病对角膜分子行为的影响。
