Department of Bionics and Bioimpedance, University of Medical Sciences, Parkowa 2, 60-775 Poznań, Poland.
Department of Physiology, University of Medical Sciences, Święcickiego 6, 60-781 Poznań, Poland.
Bioelectrochemistry. 2015 Feb;101:132-7. doi: 10.1016/j.bioelechem.2014.08.023. Epub 2014 Sep 28.
This paper aims at the presentation of the results of in vitro research on the dielectric properties of the cornea specimen collected from the rats subjected to in vivo hypothermia. The average values of the relative permittivity and dielectric loss are about 40% higher for the hypothermic cornea than those for the normothermic tissue at the same water content of 12% for both samples and at 25°C. Whereas, at 50°C this effect of increase in the dielectric properties of the hypothermic cornea when compared to the normothermic one is observed clearly only in the relative permittivity of about 19%. In the temperature range of 25-50°C, the activation energy of conductivity associated with the release of loosely bound water takes the average values of 45kJ/mol and 30kJ/mol for the normothermic and hypothermic corneas, respectively. The study provided information on dielectric polarization and conductance mechanisms in the cornea which may be helpful in interpreting clinical results of human cornea examination, currently obtained by means of such electrodiagnostic methods as conductive keratoplasty, electroretinography or electrooculography.
本文旨在介绍从接受体内低温处理的大鼠身上采集的角膜标本的体外研究结果。在相同的水含量（两种样本均为 12%）和 25°C 下，与正常体温组织相比，低温角膜的相对介电常数和介电损耗的平均值约高 40%。然而，在 50°C 下，与正常体温组织相比，低温角膜的介电性能增加的这种效应仅在相对介电常数约 19%的情况下才明显。在 25-50°C 的温度范围内，与松散结合水释放相关的电导率的激活能分别为正常角膜和低温角膜的平均 45kJ/mol 和 30kJ/mol。该研究提供了关于角膜介电极化和导电机理的信息，这可能有助于解释目前通过电诊断方法（如传导性角膜成形术、视网膜电图或眼电图）获得的人类角膜检查的临床结果。
