Goto Koji, Hatakeyama Shuji, Okamoto Koh, Kitazawa Takatoshi, Abe Katsutoshi, Moriya Kyoji, Koike Kazuhiko, Yotsuyanagi Hiroshi
Department of Internal Medicine, Infectious Diseases, Graduate School of Medicine, The University of Tokyo, Japan.
Intern Med. 2012;51(13):1779-82. doi: 10.2169/internalmedicine.51.7397. Epub 2012 Jul 1.
We report the case of a Japanese traveler who developed dengue hemorrhagic fever (DHF) with a probable secondary infection with dengue virus type 2 (DENV-2). DHF usually occurs in children, and rarely in adult travelers. Proper and timely interventions can markedly reduce the mortality rate of DHF patients. The expansion of endemic areas and increased frequency of travel to these areas may suggest increased incidence of DHF in non-endemic areas in the near future. Early recognition of reinfection with dengue virus and warning signs of circulatory failure are crucial to prevent a severe shock state.
我们报告了一例日本旅行者的病例，该旅行者患上了登革出血热（DHF），可能继发感染了2型登革病毒（DENV-2）。登革出血热通常发生在儿童中，在成年旅行者中很少见。适当及时的干预可以显著降低登革出血热患者的死亡率。流行地区的扩大以及前往这些地区旅行频率的增加可能预示着在不久的将来非流行地区登革出血热的发病率会上升。早期识别登革病毒再感染以及循环衰竭的警示信号对于预防严重休克状态至关重要。
