Ozturk Alper, Celik Yusuf
Department of General Surgery, Biruni University, Istanbul, TUR.
Department of Biostatistics and Medical Informatics, Biruni University, Istanbul, TUR.
Cureus. 2022 Aug 14;14(8):e27992. doi: 10.7759/cureus.27992. eCollection 2022 Aug.
Our research aimed to see how sleeve gastrectomy (SG) affects weight loss and comorbidities in patients with a body mass index (BMI) ≥ 50 kg/m².
Prospectively kept data of patients with a BMI ≥50 kg/m² who underwent SG between February 2016 and February 2020 were evaluated.
A total of 138 patients with a BMI ≥ 50 kg/m² were operated on. The average BMI was 56.36±7.661, the average age was 37.41±12.33. Forty-eight patients underwent concomitant cholecystectomy and/or hiatal hernia repair (HHR). The percentage of excess weight loss (EWL%) of patients at the 3rd, 6th, 12th, 18th, and 24th months were 36%, 54%, 67%, 72%, and 74%, respectively. Mean BMI values of the 0th, 3rd, 6th, 12th, 18th, and 24th months were 56, 45, 39, 35, 33, and 33, respectively. 0th, 3rd, 6th, 12th, 18th, and 24th months were significantly different for EWL%, total weight loss (TWL%), and BMI variables (p<0.001), but EWL% (p=0.527), TWL% (p=0.396) and BMI (p=0,657) were not found significantly different between the 18th and 24th months. When EWL% ≥ 50 was accepted, the success rate was 93% (n=93) and 92% (n=50) at the 18th and 24th months, respectively. While there was 82% remission in type 2 diabetes mellitus (DM) and 90% in hypertension (HT), the remission rate in patients with obstructive sleep apnea syndrome (OSAS) and gastroesophageal reflux disease (GERD) undergoing HHR was 100%.
In patients with a BMI ≥ 50 kg/m², SG seems to be an effective and safe therapy option as the first line for weight loss and treatment of comorbid diseases. Further long-term studies are needed to confirm these results.
我们的研究旨在观察袖状胃切除术（SG）对体重指数（BMI）≥50kg/m²的患者体重减轻及合并症的影响。
对2016年2月至2020年2月期间接受SG手术的BMI≥50kg/m²患者的前瞻性保存数据进行评估。
共有138例BMI≥50kg/m²的患者接受了手术。平均BMI为56.36±7.661，平均年龄为37.41±12.33。48例患者同时接受了胆囊切除术和/或食管裂孔疝修补术（HHR）。患者在第3、6、12、18和24个月时的超重体重减轻百分比（EWL%）分别为36%、54%、67%、72%和74%。第0、3、6、12、18和24个月时的平均BMI值分别为56、45、39、35、33和33。EWL%、总体重减轻（TWL%）和BMI变量在第0、3、6、12、18和24个月时有显著差异（p<0.001），但在第18和24个月时EWL%（p=0.527）、TWL%（p=0.396）和BMI（p=0.657）无显著差异。当EWL%≥50被视为成功时，第18和24个月时的成功率分别为93%（n=93）和92%（n=50）。2型糖尿病（DM）缓解率为82%，高血压（HT）缓解率为90%，接受HHR的阻塞性睡眠呼吸暂停综合征（OSAS）和胃食管反流病（GERD）患者的缓解率为100%。
对于BMI≥50kg/m²的患者，SG似乎是一种有效且安全的治疗选择，可作为减肥和治疗合并症的一线治疗方法。需要进一步的长期研究来证实这些结果。
