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1-59 月龄儿童社区获得性肺炎住院患儿的死亡危险因素:一家转诊医院的研究

Risk factors for mortality in community acquired pneumonia among children aged 1-59 months admitted in a referral hospital.

机构信息

Institute of Child Health and Hospital for Children, Egmore, Chennai, Tamilnadu, India.

出版信息

Indian Pediatr. 2012 Nov;49(11):889-95. doi: 10.1007/s13312-012-0221-3. Epub 2012 Mar 30.

Abstract

OBJECTIVE

To determine the case fatality rate and factors for death in community acquired pneumonia among children aged 1 month to 59 months admitted in a referral Hospital.

DESIGN

Hospital based retrospective study.

SETTING

Institute of Child Health and Hospital for Children, Chennai.

PATIENTS

Case records of children aged 1 month to 59 months of age with pneumonia (clinically diagnosed pneumonia, radiologically diagnosed pneumonia, and clinically and radiologically diagnosed pneumonia), from January 2006 to December 2008. Outcome measures Case fatality rate (CFR) was calculated. Risk factors for mortality analyzed were young age of 1 to 6 months old, female sex, wheeze, respiratory rate >70/min, chest indrawing, altered level of consciousness, convulsions, shock, associated heart disease, recent measles, weight for age <-2 Z score and need for assisted ventilation. The association of risk factors to mortality was arrived at for all three categories of pneumonia cases separately.

RESULTS

Case fatality rate was 8.2% (95% CI: 7.37- 8.99%). There was no significant difference in the CFR among the three study groups. Need for assisted ventilation alone was found to be an independent risk factor for mortality in children with pneumonia among all the study groups. Other risk factors like young age, weight for age <-2 Z score, altered level of consciousness, and congenital heart disease were also observed among these groups.

CONCLUSION

Among 1 month to 59 months old hospitalized children with pneumonia, CFR was 8.2%. Need for assisted ventilation was a significant risk factor associated with mortality.

摘要

目的

确定在转诊医院住院的 1 个月至 59 个月龄儿童社区获得性肺炎的病死率和死亡相关因素。

设计

医院回顾性研究。

地点

钦奈的儿童健康研究所和儿童医院。

患者

2006 年 1 月至 2008 年 12 月期间,年龄在 1 个月至 59 个月的肺炎患儿(临床诊断肺炎、放射学诊断肺炎、临床和放射学诊断肺炎)的病历。

结局指标

病死率(CFR)。分析的死亡危险因素包括 1 至 6 个月龄的幼儿、女性、喘息、呼吸频率>70/min、胸凹陷、意识改变、抽搐、休克、伴发心脏病、近期麻疹、体重年龄<-2 Z 评分和需要辅助通气。对所有三类肺炎病例分别评估危险因素与死亡率的相关性。

结果

病死率为 8.2%(95%CI:7.37-8.99%)。三组研究对象的病死率无显著差异。需要辅助通气是所有研究组中肺炎患儿死亡的独立危险因素。其他危险因素,如年龄较小、体重年龄<-2 Z 评分、意识改变和先天性心脏病,在这些组中也有观察到。

结论

在 1 个月至 59 个月龄住院肺炎患儿中,病死率为 8.2%。需要辅助通气是与死亡率相关的显著危险因素。

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