Wang Youcheng, Zhang Lijuan, Hu Guohua, Wang Menghe, Tang Xiaoyuan, Guo Hui, Shi Yimei, Chen Shufang, Shi Changchun
Jinhua People's Hospital of Zhejiang Province, Jinhua 321000, China.
Zhongguo Zhong Yao Za Zhi. 2012 Apr;37(7):1039-42.
To investigate the therapeutic effect of double fill nine tastes soup in treating children recurrent respiratory infection (RRTI) and the change of immune function.
77 RRTI patients were randomly selected into observation and control groups. The observation group was treated with Chinese medicine- double fill nine tastes soup,water frying points 2 times oral. The control was treated with transfer factor oral liquid,every 10 mL,2 times daily oral. Treatment periods were both two months. IgA, IgG, IgM and IL-12, TNF-alpha, INF-gamma were detected before and after treatment to assess the clinical effects and the changes of immune factors, meanwhile, a health group was established.
Before treatment, compared with the health group, the serum IgA, IgG, IgM, IgE, IL-12, TNF-alpha, IFN-gamma in both groups were significantly different (P < 0.01). After treatment, the ratio of IgA, IgG, Ig M, IL-12, TNF-alpha, IFN-gamma in two groups were significantly different (P < 0.01). Compared with the recurrence rate and clinical effects, the observation group was better than control, and the differences were significant (P < 0.01).
Double fill nine tastes soup has significant effects in treating recurrent respiratory infection (RRI) and enhance the immune function in children.
探讨双补九味汤治疗小儿反复呼吸道感染（RRTI）的疗效及免疫功能变化。
将77例RRTI患儿随机分为观察组和对照组。观察组采用中药双补九味汤治疗，水煎分2次口服。对照组采用转移因子口服液治疗，每次10 mL，每日2次口服。治疗疗程均为2个月。治疗前后检测IgA、IgG、IgM及IL-12、TNF-α、INF-γ，评估临床疗效及免疫因子变化，同时设立健康组。
治疗前，两组血清IgA、IgG、IgM、IgE、IL-12、TNF-α、IFN-γ与健康组比较差异均有统计学意义（P < 0.01）。治疗后，两组IgA、IgG、IgM、IL-12、TNF-α、IFN-γ比值比较差异均有统计学意义（P < 0.01）。观察组复发率及临床疗效与对照组比较，差异有统计学意义（P < 0.01），观察组优于对照组。
双补九味汤治疗小儿反复呼吸道感染（RRI）疗效显著，可提高患儿免疫功能。
