Department of Anatomy, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.
Cell Transplant. 2012;21(2-3):609-15. doi: 10.3727/096368911X605547.
It is currently said that CO has anti-inflammatory and antiapoptosis effects and it has attracted attention as a medical gas. We used CO for rat hearts and conducted a preservation experiment. We isolated rat hearts, placed them into a specially made chamber, filled the chamber with a gas mixture of PCO (4,000 hPa) and PO(2) (3,000 hPa), and preserved the hearts in a refrigerator at 4°C for 48 h. We then performed a heterotrophic transplantation on the neck of each recipient rat and resuscitated the preserved hearts. We herein report our findings.
目前有研究表明 CO 具有抗炎和抗细胞凋亡作用，作为一种医疗气体引起了人们的关注。我们使用 CO 对大鼠心脏进行了保存实验。我们将大鼠心脏分离出来，放入特制的腔室中，用 PCO（4000 hPa）和 PO₂（3000 hPa）的混合气体充满腔室，并在 4°C 的冰箱中保存心脏 48 小时。然后，我们在每个受体大鼠的颈部进行异质移植，并使保存的心脏复苏。在此，我们报告我们的发现。
