King A D, Peters A M, Stuttle A W, Lavender J P
Department of Diagnostic Radiology, Hammersmith Hospital, London, UK.
Eur J Nucl Med. 1990;17(3-4):148-51. doi: 10.1007/BF00811443.
The uptake of white blood cells (WBC) into normal bone marrow may lead to difficulty in detecting bone infection. Twenty-one patients in whom the WBC scan was equivocal or positive underwent a technetium 99m colloid scan to show the distribution of bone marrow. Six patients had a positive WBC scan, and in five of them a discordant colloid scan confirmed infection. However, in one the colloid scan was concordant, indicating that the WBC activity was not due to infection but the result of normal bone marrow uptake. Fifteen patients had an equivocal WBC scan. In 14, infection was excluded by a concordant scan, and 1 patient with a discordant scan was lost to follow-up. We conclude that the combination of a WBC scan and a colloid scan is an effective method to distinguish infection from normal bone marrow activity and, in particular, reduces the number of incorrect diagnoses of infection.
白细胞（WBC）摄取进入正常骨髓可能导致检测骨感染困难。21例白细胞扫描结果不明确或呈阳性的患者接受了锝99m胶体扫描以显示骨髓分布。6例患者白细胞扫描呈阳性，其中5例胶体扫描结果不一致证实存在感染。然而，1例患者胶体扫描结果一致，表明白细胞活性并非由感染引起，而是正常骨髓摄取的结果。15例患者白细胞扫描结果不明确。其中14例通过一致的扫描排除了感染，1例扫描结果不一致的患者失访。我们得出结论，白细胞扫描和胶体扫描相结合是区分感染与正常骨髓活性的有效方法，尤其减少了感染误诊的数量。
