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对比研究切口并发症:单纯行腹皮瓣切除术与腹皮瓣切除术联合腹疝修补术。

Comparative study of wound complications: isolated panniculectomy versus panniculectomy combined with ventral hernia repair.

机构信息

Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Laparoscopic and Advanced Surgery Program, Charlotte, North Carolina, USA.

出版信息

J Surg Res. 2012 Oct;177(2):387-91. doi: 10.1016/j.jss.2012.06.029. Epub 2012 Jul 6.

Abstract

BACKGROUND

The resection of an abdominal pannus carries the risk of wound-related morbidity in obese patients. Surgeons often perform a panniculectomy (PAN) to gain better access to the abdomen to perform other operations. We evaluated the incidence of wound complications after PAN with and without a concomitant procedure (i.e., ventral hernia repair [VHR]).

METHODS

We reviewed the prospective data from all patients who underwent PAN alone and PAN combined with VHR from 2007 to 2011 at a single institution. The demographic data, operative information, and postoperative wound complications and interventions were recorded and analyzed using standard statistical methods. Multivariate logistic regression analysis was performed to control for confounding factors.

RESULTS

After excluding the patients who had undergone concomitant procedures involving the gastrointestinal or genitourinary tract, 185 patients were included in the present study (143 patients in the PAN-VHR group and 42 in the PAN group). The average patient age was 55.4 and 47.6 years in the two groups (P = 0.001). The average body mass index was 38.0 and 41.1 kg/m(2) (P = 0.69). Of the 143 patients in the PAN-VHR group, 81.1% were women. In the PAN group, 92.9% were women (P = 0.09). The mean length of follow-up was 6.5 and 3.3 mo in the PAN-VHR and PAN groups, respectively (P = 0.04). In the PAN-VHR group, 96.5% underwent hernia repair with mesh and 29% underwent component separation. Subcutaneous talc was used in 58.6% of the PAN-VHR patients and 38.1% of the PAN patients (P = 0.02). Wound pulse-a-vac irrigation with bacitracin solution was used in 37.1% of PAN-VHR patients and 19.1% of the PAN patients (P = 0.03). The rate of wound complications and interventions for the PAN-VHR and PAN groups were not significantly different statistically (P < 0.05) and included seroma, seroma drainage, wound breakdown or necrosis, cellulitis, wound interventions, including bedside debridement and vac placement, and reoperation. After controlling for age, gender, body mass index, talc use, and pulse-a-vac irrigation use in the multivariate logistic regression analysis, the PAN-VHR group were more likely to develop cellulitis than the PAN-alone group (P = 0.004). The rates of all other wound complications were not significantly different statistically between the two groups after adjusting for confounding factors.

CONCLUSIONS

PAN is associated with a significant risk of wound-related complications. The risk of postoperative cellulitis is increased further in patients who undergo concomitant VHR. However, the risk of all other wound complications and the need for interventions was not increased by performing concomitant VHR.

摘要

背景

腹部脂肪垂切除术会增加肥胖患者的伤口相关并发症风险。外科医生通常会进行脂肪垂切除术(PAN),以获得更好的腹部手术通道。我们评估了 PAN 术和同时进行的腹疝修补术(VHR)后伤口并发症的发生率。

方法

我们回顾了 2007 年至 2011 年在一家医院进行的单纯 PAN 术和 PAN 术联合 VHR 术的所有患者的前瞻性数据。记录人口统计学数据、手术信息以及术后伤口并发症和干预措施,并使用标准统计方法进行分析。采用多变量逻辑回归分析控制混杂因素。

结果

排除胃肠道或泌尿生殖道相关联合手术的患者后,本研究共纳入 185 例患者(PAN-VHR 组 143 例,PAN 组 42 例)。两组患者的平均年龄分别为 55.4 岁和 47.6 岁(P=0.001)。两组患者的平均 BMI 分别为 38.0 kg/m²和 41.1 kg/m²(P=0.69)。PAN-VHR 组 143 例患者中,81.1%为女性,PAN 组中 92.9%为女性(P=0.09)。PAN-VHR 组和 PAN 组的平均随访时间分别为 6.5 个月和 3.3 个月(P=0.04)。PAN-VHR 组中,96.5%的患者接受了网片修补术,29%的患者接受了补片分离术。PAN-VHR 组中 58.6%的患者和 PAN 组中 38.1%的患者使用了滑石粉(P=0.02)。PAN-VHR 组中 37.1%的患者和 PAN 组中 19.1%的患者使用了 bacitracin 溶液脉冲式伤口负压吸引冲洗(P=0.03)。PAN-VHR 组和 PAN 组的伤口并发症和干预措施发生率无统计学差异(P<0.05),包括血清肿、血清肿引流、伤口破裂或坏死、蜂窝织炎、伤口干预,包括床边清创和 vac 置管以及再次手术。在多变量逻辑回归分析中控制年龄、性别、BMI、滑石粉使用和脉冲式伤口负压吸引冲洗使用等混杂因素后,PAN-VHR 组发生蜂窝织炎的风险高于单纯 PAN 组(P=0.004)。调整混杂因素后,两组间所有其他伤口并发症的发生率无统计学差异。

结论

PAN 术与伤口相关并发症的发生风险显著相关。同时进行 VHR 术会增加术后蜂窝织炎的风险。然而,同时进行 VHR 术并不会增加其他伤口并发症的风险或需要进行干预。

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