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打破周末趋势:老年创伤性脑损伤(TBI)患者周末入院死亡率增加。

Beating the weekend trend: increased mortality in older adult traumatic brain injury (TBI) patients admitted on weekends.

机构信息

Department of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

出版信息

J Surg Res. 2012 Oct;177(2):295-300. doi: 10.1016/j.jss.2012.06.022. Epub 2012 Jul 7.

Abstract

BACKGROUND

Weekend admission is associated with mortality in cardiovascular emergencies and stroke but the effect of weekend admission for trauma is not well defined. We sought to determine whether differences in mortality outcomes existed for older adults with substantial head trauma admitted on a weekday versus over the weekend.

METHODS

Data from the 2006, 2007, and 2008 Nationwide Inpatient Sample were combined and head trauma admissions were isolated. Abbreviated injury scale (AIS) scores were calculated using ICDMAP-90 Software. Individuals aged 65 to 89 y with head AIS equal to 3 or 4 and no other region score <3 were included. Individual Charlson comorbidity scores were calculated and individuals with missing mortality, sex, or insurance data were excluded. Wilcoxon rank sum and Student t-tests compared demographics, length of stay, and total charges for weekday versus weekend admissions. The χ2 tests compared sex and head injury severity. Logistic regression modeled mortality adjusting for age, sex, injury severity, comorbidity, and insurance status.

RESULTS

Of the 38,675 patients meeting criteria, 9937 (25.6%) were admitted on weekends. Mean age was similar (78.4 versus 78.4, P = 0.796) but more weekend admissions were female (51.6% versus 50.2%, P = 0.022). Weekend patients demonstrated slightly lower comorbidity (mean Charlson = 1.07 versus 1.14, P < 0.001) and head injury severity (58.3% versus 60.8% AIS = 4, P < 0.001). Median weekend length of stay was shorter (4 versus 5 d, P < 0.001). Weekend and weekday median total charges did not differ ($27,128 versus $27,703, respectively, P = 0.667). Proportional mortality was higher among weekend patients (9.3% versus 8.4%, P = 0.008). After adjustment, weekend patients demonstrated 14% increased odds of mortality (OR 1.14, 95% CI 1.05-1.23).

CONCLUSION

Older adults with substantial head trauma admitted on weekends are less severely injured, carry less comorbidity, and generate similar total charges compared with those admitted on weekdays. However, after accounting for known risk confounders, weekend patients demonstrated 14% greater odds of mortality. Mechanisms behind this disparity must be determined and eliminated.

摘要

背景

周末入院与心血管急症和中风患者的死亡率相关,但创伤患者周末入院的影响尚未明确。我们旨在确定对于因严重头部创伤而入院的老年人,在工作日与周末入院的死亡率是否存在差异。

方法

将 2006 年、2007 年和 2008 年全国住院患者样本的数据合并,并分离出头部创伤患者。使用 ICDMAP-90 软件计算简明损伤量表(AIS)评分。纳入年龄在 65 至 89 岁之间,头部 AIS 等于 3 或 4 且无其他区域评分<3 的患者。计算个人 Charlson 合并症评分,并排除死亡率、性别或保险数据缺失的个体。Wilcoxon 秩和检验和学生 t 检验比较工作日与周末入院的人口统计学、住院时间和总费用。卡方检验比较性别和头部损伤严重程度。使用 logistic 回归模型,根据年龄、性别、损伤严重程度、合并症和保险状况调整死亡率。

结果

在符合条件的 38675 名患者中,有 9937 名(25.6%)在周末入院。平均年龄相似(78.4 岁对 78.4 岁,P=0.796),但周末入院的女性比例更高(51.6%对 50.2%,P=0.022)。周末患者的合并症略低(平均 Charlson 为 1.07 对 1.14,P<0.001),头部损伤严重程度也较低(58.3%对 60.8%的 AIS=4,P<0.001)。周末的中位住院时间更短(4 天对 5 天,P<0.001)。周末和工作日的中位总费用无差异(分别为 27128 美元和 27703 美元,P=0.667)。周末患者的比例死亡率较高(9.3%对 8.4%,P=0.008)。调整后,周末患者的死亡率增加了 14%(OR 1.14,95%CI 1.05-1.23)。

结论

与在工作日入院的患者相比,因严重头部创伤而在周末入院的老年人损伤程度较轻,合并症较少,总费用相似。然而,在考虑到已知的风险混杂因素后,周末患者的死亡率增加了 14%。必须确定并消除这种差异背后的机制。

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