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严重创伤性脑损伤是否存在周末效应?一项基于挪威创伤登记处的观察性人群研究。

Is there a weekend effect in severe traumatic brain Injury? An observational, population-based study from the Norwegian Trauma registry.

作者信息

Andreassen Joakim Stray, Madsbu Mattis A, Werner David Andreas Thomas, Weber Clemens

机构信息

Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Norway.

出版信息

Brain Spine. 2025 Apr 28;5:104263. doi: 10.1016/j.bas.2025.104263. eCollection 2025.

DOI:10.1016/j.bas.2025.104263
PMID:40476155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12138575/
Abstract

INTRODUCTION

Traumatic brain injury is prevalent and with severe injury the mortality is high. The aim of this study was to explore differences in mortality rates between weekday and weekend admissions for patients with severe traumatic brain injury (TBI) in Norway based on data from the National Trauma Registry of Norway (NTR).

RESEARCH QUESTION

Are mortality rates higher for patients with severe traumatic brain injury admitted on weekends compared to weekdays?

MATERIALS AND METHODS

This study is an observational cohort study based on prospectively collected, population-based data from the NTR. The study period was between January 01, 2017 and December 31, 2020 and included all patients with severe TBI registered in the database.

RESULTS

During the 4 years-study period 627 patients with severe TBI were identified; the median age was 53.0 years (IQR 32.0-71.0). Weekend admissions involved significantly younger patients with a median age of 50.0 years compared to a median age of 57.0 years on weekdays (p = 0.013). Overall, the 30-day mortality rate was 39 %, with higher mortality observed on weekdays compared to weekends (43 % vs. 34 %; p = 0.025). Logistic regression analysis showed that age and higher AIS head injury severity were significantly associated with 30-day mortality, while admission timing (weekend vs. weekday) showed no association.

DISCUSSION AND CONCLUSION

Weekend admissions in severe TBI are frequent and involves younger patients compared to weekdays. Our study did not find a weekend effect on the mortality rate for severe TBI in Norway based on data from the NTR.

摘要

引言

创伤性脑损伤很常见,严重损伤时死亡率很高。本研究的目的是基于挪威国家创伤登记处(NTR)的数据,探讨挪威重度创伤性脑损伤(TBI)患者在工作日和周末入院的死亡率差异。

研究问题

与工作日入院的重度创伤性脑损伤患者相比,周末入院患者的死亡率是否更高?

材料与方法

本研究是一项观察性队列研究,基于NTR前瞻性收集的基于人群的数据。研究期间为2017年1月1日至2020年12月31日,纳入数据库中登记的所有重度TBI患者。

结果

在4年的研究期间,共识别出627例重度TBI患者;中位年龄为53.0岁(四分位间距32.0 - 71.0)。周末入院的患者明显更年轻,中位年龄为50.0岁,而工作日入院患者的中位年龄为57.0岁(p = 0.013)。总体而言,30天死亡率为39%,工作日的死亡率高于周末(43%对34%;p = 0.025)。逻辑回归分析表明,年龄和较高的AIS头部损伤严重程度与30天死亡率显著相关,而入院时间(周末与工作日)则无关联。

讨论与结论

重度TBI患者周末入院情况较为频繁,且与工作日相比涉及更年轻的患者。基于NTR的数据,我们的研究未发现挪威重度TBI的死亡率存在周末效应。

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Excellent agreement of Norwegian trauma registry data compared to corresponding data in electronic patient records.挪威创伤登记处的数据与电子患者记录中的相应数据吻合良好。
Scand J Trauma Resusc Emerg Med. 2023 Sep 26;31(1):50. doi: 10.1186/s13049-023-01118-5.
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Weekend effect on 30-day mortality for ischemic and hemorrhagic stroke analyzed using severity index and staffing level.利用严重程度指数和人员配备水平分析缺血性和出血性卒中 30 天死亡率的周末效应。
PLoS One. 2023 Jun 22;18(6):e0283491. doi: 10.1371/journal.pone.0283491. eCollection 2023.
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The off-hour effect on mortality in traumatic brain injury according to age group.创伤性脑损伤患者按年龄组划分的非工作时间效应与死亡率的关系。
PLoS One. 2023 Mar 16;18(3):e0282953. doi: 10.1371/journal.pone.0282953. eCollection 2023.
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