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左心室动态网格的人类流体动力学建模:正常和心肌梗死的初步研究。

Fluid-dynamics modelling of the human left ventricle with dynamic mesh for normal and myocardial infarction: preliminary study.

机构信息

School of Mechanical and Aerospace Engineering, College of Engineering, Nanyang Technological University, Singapore, Singapore.

出版信息

Comput Biol Med. 2012 Aug;42(8):863-70. doi: 10.1016/j.compbiomed.2012.06.010. Epub 2012 Jul 12.

Abstract

Pulsating blood flow patterns in the left ventricular (LV) were computed for three normal subjects and three patients after myocardial infarction (MI). Cardiac magnetic resonance (MR) images were obtained, segmented and transformed into 25 frames of LV for a computational fluid dynamics (CFD) study. Multi-block structure meshes were generated for 25 frames and 75 intermediate grids. The complete LV cycle was modelled by using ANSYS-CFX 12. The flow patterns and pressure drops in the LV chamber of this study provided some useful information on intra-LV flow patterns with heart diseases.

摘要

为 3 名正常受试者和 3 名心肌梗死 (MI) 患者计算了左心室 (LV) 的脉动血流模式。获得心脏磁共振 (MR) 图像,对其进行分割并转换为 LV 的 25 个帧,以进行计算流体动力学 (CFD) 研究。为 25 个帧和 75 个中间网格生成了多块结构网格。使用 ANSYS-CFX 12 对整个 LV 周期进行建模。本研究中 LV 腔室内的流动模式和压降提供了一些有关心脏病患者 LV 内流动模式的有用信息。

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