Department of Orthopaedic Surgery, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Arthroplasty. 2013 Feb;28(2):315-322.e2. doi: 10.1016/j.arth.2012.04.027. Epub 2012 Jul 13.
We prospectively measured functional performances (Western Ontario and McMaster Universities Osteoarthritis Index, Short Form-36, 2-minute walk test, and timed get-up-and-go test) of patients who underwent total hip arthroplasty (THA) and had serum vitamin D levels tested during the preoperative evaluation. Of 219 patients, 102 (46.6%) had low vitamin D levels (25-hydroxyvitamin D<30 ng/mL). Low vitamin D status did not adversely affect short-term function at 6 weeks after THA. In addition, there was no association between serum vitamin D levels and the within-patient changes of scores of each outcome measurement. Because this 6-week period is generally adequate to correct vitamin D deficiency, orthopedic surgeons can safely perform THA without delay. Nevertheless, because vitamin D deficiency impairs bone quality, patients with low vitamin D levels should be treated once identified.
我们前瞻性地测量了接受全髋关节置换术（THA）的患者的功能表现（安大略西部和麦克马斯特大学骨关节炎指数、简短表格 36、2 分钟步行测试和计时起身行走测试），并在术前评估期间检测了血清维生素 D 水平。在 219 名患者中，有 102 名（46.6%）维生素 D 水平较低（25-羟维生素 D<30ng/mL）。低维生素 D 状态不会对 THA 后 6 周的短期功能产生不利影响。此外，血清维生素 D 水平与每个结果测量评分的患者内变化之间没有关联。由于这段 6 周的时间通常足以纠正维生素 D 缺乏，因此骨科医生可以安全地延迟进行 THA。然而，由于维生素 D 缺乏会损害骨质量，因此一旦发现低维生素 D 水平的患者，应进行治疗。
