下肢关节置换术中维生素D缺乏症：一项系统评价和荟萃分析。
Hypovitaminosis D in lower extremity Joint Arthroplasty: A systematic review and meta-analysis.
作者信息
Emara Ahmed K, Nageeb Emmanuel, George Jaiben, Buttaro Martin A, Higuera Carlos, Piuzzi Nicolas S
机构信息
Cleveland Clinic, Department of Orthopedic Surgery, 9500 Euclid Ave/A41, Cleveland, OH, 44195, USA.
Hip Surgery Unit "Sir John Charnley", Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
出版信息
J Orthop. 2020 Mar 25;21:109-116. doi: 10.1016/j.jor.2020.03.010. eCollection 2020 Sep-Oct.
Abstract
UNLABELLED
The purpose of the current systematic review was to identify the prevalence of hypovitaminosis-D in LE-TJA patients; and outline the association between pre-operative hypovitaminosis and post-operative outcomes. A search of PubMed-Medline and the Cochrane-Library databases was performed for literature published before November 27th, 2019 The eighteen studies analyzed had a pooled prevalence for vitamin D insufficiency (20 - <30 ng/mL) and deficiency (<20 ng/mL) of 53.4% and 39.4%, respectively. Hypovitaminosis-D was associated with higher complication rates ( = 0.043), and a greater prevalence among septic versus aseptic revisions ( = 0.016). Therefore, pre-operative screening for hypovitaminosis-D can be beneficial in patients undergoing LE-TJA.
LEVEL OF EVIDENCE
Systematic Review (Level III).
摘要
未标注
本系统评价的目的是确定全膝关节置换术（LE-TJA）患者维生素D缺乏症的患病率；并概述术前维生素D缺乏与术后结果之间的关联。检索了PubMed-Medline和Cochrane图书馆数据库，以查找2019年11月27日前发表的文献。分析的18项研究中，维生素D不足（20 - <30 ng/mL）和缺乏（<20 ng/mL）的合并患病率分别为53.4%和39.4%。维生素D缺乏与较高的并发症发生率相关（P = 0.043），并且在感染性翻修与无菌性翻修中的患病率更高（P = 0.016）。因此，对接受LE-TJA的患者进行术前维生素D缺乏症筛查可能有益。
证据级别
系统评价（III级）。
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