POEMS综合征——一种罕见副肿瘤综合征的独特表现。
POEMS syndrome - a unique presentation of a rare paraneoplastic syndrome.
作者信息
Livingston J, Cobiella C, Hall-Craggs M A
机构信息
Accident and Emergency Department, Basildon and Thurrock University Hospital, Nethermayne, Essex, UK.
出版信息
BMJ Case Rep. 2010 Dec 1;2010:bcr0920103324. doi: 10.1136/bcr.09.2010.3324.
Abstract
POEMS (peripheral neuropathy, organomegaly, endocrinopathy, M protein, skin changes) syndrome is a rare multisystem paraneoplastic disorder. A 40-year-old male with a history of peripheral neuropathy and erectile dysfunction presented with a pathological fracture of the neck of the femur, found to be a solitary plasmacytoma. Additional unusual features included splenomegaly, hyperprolactinaemia and skin changes. The patient had a total hip replacement at a specialist orthopaedic hospital and is due to undergo radiotherapy to the femoral lesion and autologous stem cell transplantation.
摘要
POEMS（周围神经病变、脏器肿大、内分泌病、M蛋白、皮肤改变）综合征是一种罕见的多系统副肿瘤性疾病。一名有周围神经病变和勃起功能障碍病史的40岁男性因股骨颈病理性骨折就诊，被发现患有孤立性浆细胞瘤。其他不寻常的特征包括脾肿大、高催乳素血症和皮肤改变。该患者在一家专业骨科医院接受了全髋关节置换术，随后将对股骨病变进行放疗并接受自体干细胞移植。
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