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（4E）-N-[(2-氯苯基)甲氧基]-1,3-二甲基-2,6-二苯基哌啶-4-亚胺

(4E)-N-[(2-Chloro-phen-yl)meth-oxy]-1,3-dimethyl-2,6-diphenyl-piperidin-4-imine.

作者信息

Ramalingan Chennan, Ng Seik Weng, Tiekink Edward R T

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2268. doi: 10.1107/S1600536812028899. Epub 2012 Jun 30.

DOI:10.1107/S1600536812028899
PMID:22798916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3394051/
Abstract

In the title compound, C(26)H(27)ClN(2)O, the piperidine ring has a chair conformation and all of the ring substituents at Csp(3) atoms occupy equatorial positions. The dihedral angle formed between the phenyl rings is 48.11 (9)°. The chloro-benzene ring occupies a position orthogonal to the meth-oxy(methyl-idene)amine residue [N-O-C-C torsion angle = -87.90 (15)°]. The conformation about the imine C=N bond [1.278 (2) Å] is E, and the chloro substituent is anti to the piperidine N atom. Helical supra-molecular chains along [010] are sustained by C-H⋯π inter-actions in the crystal packing.

摘要

在标题化合物C(26)H(27)ClN(2)O中，哌啶环呈椅式构象，且Csp(3)原子上的所有环取代基均占据赤道位置。苯环之间形成的二面角为48.11 (9)°。氯苯环占据与甲氧基(亚甲基)胺残基正交的位置[N-O-C-C扭转角 = -87.90 (15)°]。亚胺C=N键[1.278 (2) Å]的构象为E型，氯取代基与哌啶N原子呈反式。在晶体堆积中，沿着[010]方向的螺旋超分子链由C-H⋯π相互作用维持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/ba76676d5ac8/e-68-o2268-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/4b5b0f0d8af3/e-68-o2268-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/e4c55251ca21/e-68-o2268-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/ba76676d5ac8/e-68-o2268-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/4b5b0f0d8af3/e-68-o2268-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/e4c55251ca21/e-68-o2268-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef6/3394051/ba76676d5ac8/e-68-o2268-fig3.jpg

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