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中国大陆自杀行为相关因素的 Meta 分析。

Factors associated with suicidal behaviors in mainland China: a meta-analysis.

机构信息

Department of Social Medicine and Health Service Management, College of Preventive Medicine, Third Military Medical University, No.30 Gaotanyan Road, Shapingba District, Chongqing, People’s Republic of China.

出版信息

BMC Public Health. 2012 Jul 16;12:524. doi: 10.1186/1471-2458-12-524.

Abstract

BACKGROUND

Suicide is a major public health issue in China. Studies of suicide risk factors have reported both inconsistent and inconclusive results. This review aimed to determine suicide risk factors in China.

METHODS

Medline/PubMed, EMBASE, CNKI (China National Knowledge Infrastructure) and VIP (Chinese Journal of Science and Technology of VIP) were searched for relevant reports. Two investigators independently assessed the eligibility of identified studies and extracted data. Pooled odds ratios (and 95% confidence intervals) were calculated for each factor with Revman 5.0.

RESULTS

Forty-four studies with 192,362 subjects were included. The pooled results indicated that mood disorders and stressful life events (physical illness, suicide of relatives) increased the risk of suicide ideation among the entire population. Socio-family environment (single or remarried parent, study pressure and academic achievement) and unhealthy behaviors (smoking, alcohol drinking, and drug use) were risk factors for suicide ideation among youth. Unhealthy behaviors (smoking and alcohol drinking), mood disorders, and stressful life events (suicide of relatives) were the main risk factors for attempted suicide. Persons living in rural areas, and those with lower education, mood disorders, and/or a history of negative life events had a higher risk of completed suicide. In China, before 2000, females had a significantly higher rate of completed suicide than males, while after 2000, no significant gender difference was found.

CONCLUSIONS

Socio-family environment, lifestyle, life events and psychiatric/psychological factors are associated with suicidal behaviors in China. Further case-control or cohort studies are needed to better understand suicide behaviors in China. Meanwhile, there is an urgent need for comprehensive studies of suicide interventions among high-risk populations.

摘要

背景

自杀是中国的一个主要公共卫生问题。关于自杀风险因素的研究报告结果既有不一致的情况,也有不明确的情况。本综述旨在确定中国的自杀风险因素。

方法

检索了 Medline/PubMed、EMBASE、中国知网(CNKI)和维普中文科技期刊数据库(VIP),以获取相关报告。两名调查员独立评估确定研究的资格,并提取数据。使用 Revman 5.0 计算每个因素的合并优势比(和 95%置信区间)。

结果

共纳入 44 项研究,涉及 192362 名受试者。汇总结果表明,心境障碍和生活应激事件(躯体疾病、亲属自杀)增加了全人群自杀意念的风险。社会家庭环境(单亲或再婚父母、学习压力和学业成绩)和不健康行为(吸烟、饮酒和药物使用)是青少年自杀意念的危险因素。不健康行为(吸烟和饮酒)、心境障碍和生活应激事件(亲属自杀)是自杀未遂的主要危险因素。居住在农村地区的人、受教育程度较低的人、有心境障碍和/或有负性生活事件史的人,自杀的风险更高。在中国,2000 年之前,女性自杀的比率明显高于男性,而 2000 年之后,男女之间没有显著差异。

结论

社会家庭环境、生活方式、生活事件和精神心理因素与中国的自杀行为有关。需要进一步开展病例对照或队列研究,以更好地了解中国的自杀行为。同时,迫切需要对高危人群的自杀干预进行全面研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6c/3490836/1a7ebe50cecf/1471-2458-12-524-1.jpg

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