Currier Dianne, Spittal Matthew J, Patton George, Pirkis Jane
Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, 3010, Australia.
Centre for Mental Health, The University of Melbourne, Melbourne, 3010, Australia.
BMC Public Health. 2016 Oct 31;16(Suppl 3):1031. doi: 10.1186/s12889-016-3702-9.
Suicide is a leading cause of death in Australian males aged 18 to 55. Non-fatal suicidal behaviours and thoughts are indicators of increased risk for future suicide. Suicidal behaviour is complex and multi-determined. Research supports the involvement of stressful life events in suicide and suicidal behaviour, however the evidence regarding suicidal thoughts is less developed. This study investigates stressful life events in relation to suicidal ideation in a large cohort of adult males recruited into Ten to Men, the Australian Longitudinal Study on Male Health.
Baseline data from a national cohort of 13, 884 males aged 18-55 years on suicidal behaviour, psychiatric disorder and life events was used. Multivariable logistic regressions were conducted with current suicidal ideation as the outcome and 12 month life events, 12 month depression, anxiety and harmful/hazardous alcohol use, and socio-demographics as covariates. Further logistic regression models investigated the relative risk of life stress alone, depression/alcohol/anxiety alone and co-occurring life stress and depression/alcohol/anxiety.
In multivariable models there was an independent contribution to suicidal ideation for six of 24 life events (ORs 1.27-1.95), 12 month depression (OR 4.49) harmful alcohol use (OR 1.38) and anxiety disorders (OR 1.27). Life events co-occurring with depression (OR 10.3) was higher risk than either alone (depression OR 6.6; life stress OR 2.6). There was a lesser effect for co-occurrence in the anxiety and harmful alcohol use models.
Life events appear to be related to suicidal ideation independent of depression, anxiety and harmful alcohol use in adult males, however if life events occur in the context of depression that risk is substantially increased.
自杀是澳大利亚18至55岁男性的主要死因。非致命性自杀行为和想法是未来自杀风险增加的指标。自杀行为复杂且由多种因素决定。研究支持生活应激事件与自杀及自杀行为有关,然而关于自杀想法的证据尚不充分。本研究在纳入澳大利亚男性健康纵向研究“十到男人”的大量成年男性队列中,调查与自杀意念相关的生活应激事件。
使用来自一个全国性队列的13884名18 - 55岁男性的基线数据,这些数据涉及自杀行为、精神疾病和生活事件。以当前自杀意念为结果,以12个月的生活事件、12个月的抑郁、焦虑以及有害/危险饮酒情况,和社会人口统计学特征作为协变量,进行多变量逻辑回归分析。进一步的逻辑回归模型研究了单独生活压力、单独抑郁/酒精/焦虑以及生活压力与抑郁/酒精/焦虑共同出现时的相对风险。
在多变量模型中,24种生活事件中的6种(比值比为1.27 - 1.95)、12个月的抑郁(比值比为4.49)、有害饮酒(比值比为1.38)和焦虑症(比值比为1.27)对自杀意念有独立影响。与抑郁共同出现的生活事件(比值比为10.3)比单独出现时风险更高(抑郁比值比为6.6;生活压力比值比为2.6)。在焦虑和有害饮酒模型中,共同出现的影响较小。
生活事件似乎与成年男性的自杀意念有关,独立于抑郁、焦虑和有害饮酒,然而如果生活事件发生在抑郁背景下,风险会大幅增加。