National Research Laboratory for Organic Opto-electronic Materials, Department of Chemical and Biomolecular Engineering-BK-21, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
Nanotechnology. 2012 Aug 10;23(31):315302. doi: 10.1088/0957-4484/23/31/315302.
We fabricated a regular array of Ag/SiO₂/Au multi-segment cylindrical nanopatterns to create a highly efficient surface enhanced Raman scattering (SERS) active substrate using an advanced soft-nanoimprint lithographic technique. The SERS spectra results for Rhodamine 6G (R6G) molecules on the Ag/SiO₂/Au multi-segment nanopatterns show that the highly ordered patterns and interlayer thickness are responsible for enhancing the sensitivity and reproducibility, respectively, The multi-segment nanopattern with a silica interlayer generates significant SERS enhancement (EF = 1.2 x 10⁶) as compared to that of the bimetallic (Ag/Au) nanopatterns without a dielectric gap (EF = 1.0 x 10⁴). Further precise control of the interlayer distances between the two metals plays an essential role in enhancing SERS performance for detecting low concentrations of analytes such as fluorescent (Rhodamine 6G) and DNA molecules. Therefore, the highly ordered multi-segment patterns provide great sensitivity and reproducibility of SERS based detection, resulting in a high performance of the SERS substrate.
我们使用先进的软纳米压印光刻技术，制造了 Ag/SiO₂/Au 多段圆柱纳米图案的规则阵列，以创建高效的表面增强拉曼散射（SERS）活性基底。在 Ag/SiO₂/Au 多段纳米图案上的 Rhodamine 6G（R6G）分子的 SERS 光谱结果表明，高度有序的图案和层间厚度分别负责提高灵敏度和重现性。与没有介电间隙的双金属（Ag/Au）纳米图案（EF = 1.0 x 10⁴）相比，具有二氧化硅层间的多段纳米图案产生了显著的 SERS 增强（EF = 1.2 x 10⁶）。进一步精确控制两种金属之间的层间距离对于增强用于检测低浓度分析物（如荧光（Rhodamine 6G）和 DNA 分子）的 SERS 性能起着至关重要的作用。因此，高度有序的多段图案提供了基于 SERS 的检测的高灵敏度和重现性，从而实现了 SERS 基底的高性能。
