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一名白化病女性的无色素性恶性黑色素瘤。

Nevoid malignant melanoma in an albino woman.

作者信息

Binesh F, Akhavan A, Navabii H

机构信息

Department of Pathology, Shahid Sadoghi Hospital, Yazd Shahid Sadoghi University, Yazd, Iran.

出版信息

BMJ Case Rep. 2010 Dec 6;2010:bcr0820103262. doi: 10.1136/bcr.08.2010.3262.

Abstract

Albinism is a disorder of hypopigmentation affecting the skin, hair and eyes. Ultraviolet light induced cutaneous tumours are common in patients with albinism due to reduced or absent protection from melanin, with squamous cell carcinoma being the most common. Although non-melanomatous skin cancers are more frequent in patients with albinism, dysplastic nevi and melanoma present a greater diagnostic challenge in this group because of their hypopigmented appearance. Here the authors report a case of nevoid malignant melanoma in a patient who had type 1A oculocutaneous albinism.

摘要

白化病是一种影响皮肤、头发和眼睛的色素减退性疾病。由于黑色素的保护作用减弱或缺失,紫外线诱导的皮肤肿瘤在白化病患者中很常见,其中鳞状细胞癌最为常见。虽然非黑素瘤性皮肤癌在白化病患者中更为常见,但发育异常痣和黑色素瘤在该群体中因其色素减退的外观而带来更大的诊断挑战。在此,作者报告了一例患有1A型眼皮肤白化病患者的痣样恶性黑色素瘤病例。

相似文献

1
Nevoid malignant melanoma in an albino woman.一名白化病女性的无色素性恶性黑色素瘤。
BMJ Case Rep. 2010 Dec 6;2010:bcr0820103262. doi: 10.1136/bcr.08.2010.3262.
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Malignant melanoma in a child with oculocutaneous albinism.
J Surg Oncol. 1992 Oct;51(2):138-42. doi: 10.1002/jso.2930510215.

本文引用的文献

4
Molecular basis of oculocutaneous albinism.眼皮肤白化病的分子基础。
J Invest Dermatol. 1994 Nov;103(5 Suppl):131S-136S. doi: 10.1111/1523-1747.ep12399447.
7
Albinism.白化病。
Dermatol Clin. 1988 Apr;6(2):217-28.
8
Biology of hypopigmentation.色素减退的生物学
J Am Acad Dermatol. 1988 Aug;19(2 Pt 1):217-55. doi: 10.1016/s0190-9622(88)70168-1.
9
Primary malignant melanoma of the lung.
Am Rev Respir Dis. 1989 Jun;139(6):1543-7. doi: 10.1164/ajrccm/139.6.1543.

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