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分诊生命体征与血清乳酸或碱缺失不相关,对穿透性创伤患者的手术干预预测性较差:一项前瞻性队列研究。

Triage vital signs do not correlate with serum lactate or base deficit, and are less predictive of operative intervention in penetrating trauma patients: a prospective cohort study.

机构信息

Department of Emergency Medicine, Lincoln Medical and Mental Health Center, 234 east 149 Street, Bronx, NY 10451, USA.

出版信息

Emerg Med J. 2013 Jul;30(7):546-50. doi: 10.1136/emermed-2012-201343. Epub 2012 Jul 16.

Abstract

BACKGROUND

Triage vital signs are often used to help determine a trauma patient's haemodynamic status. Recent studies have demonstrated that these may not be very specific in determining major injury. The purpose of this study was to determine if there is any correlation between triage vital signs, base deficit (BD) and lactate, and to determine the odds of operative intervention in penetrating trauma patients.

METHODS

A prospective observational cohort study was undertaken. Baseline vital signs, BD and lactate were recorded in all patients for whom the trauma team was activated. Pearson correlation and coefficient (ρ) were calculated. ORs were calculated.

RESULTS

75 patients were enrolled. Pearson correlations and coefficients calculated for lactate to systolic blood pressure were: -0.052 (ρ=0.0011, 95% CI -0.225 to 0.228); lactate and HR: 0.23 (ρ=0.0166, 95% CI -0.211 to 0.242); lactate and RR: 0.23 (ρ=0.054, 95% CI -0.174 to 0.277). BD to systolic blood pressure were: 0.003 (ρ=0.00001, 95% CI -0.229 to 0.224); BD and HR: -0.19 (ρ=0.038, 95% CI -0.399 to 0.038); BD and RR: -0.019 (ρ=0.0004, 95% CI -0.244 to 0.208). Odds of operative intervention were greater in patients with abnormally high lactate, OR 4.17 (95% CI 1.57 to 11), but not for BD, OR 2.53 (95% CI 0.99 to 6.45), or any of the vital signs.

CONCLUSIONS

Triage vital signs have no correlation to lactate or BD levels in penetrating trauma patients. Odds of operative intervention are greater in patients with abnormally high serum lactate levels, but not in those with abnormal triage vital signs or BD.

摘要

背景

分诊生命体征常用于帮助确定创伤患者的血流动力学状态。最近的研究表明,这些指标在确定严重损伤方面可能不是很特异。本研究旨在确定分诊生命体征、碱缺失(BD)和乳酸之间是否存在相关性,并确定穿透性创伤患者手术干预的可能性。

方法

进行了一项前瞻性观察队列研究。对所有激活创伤团队的患者记录基线生命体征、BD 和乳酸。计算 Pearson 相关系数(ρ)和系数。计算比值比(OR)。

结果

共纳入 75 例患者。计算乳酸与收缩压的 Pearson 相关系数和系数为:-0.052(ρ=0.0011,95%CI-0.225 至 0.228);乳酸与 HR:0.23(ρ=0.0166,95%CI-0.211 至 0.242);乳酸与 RR:0.23(ρ=0.054,95%CI-0.174 至 0.277)。BD 与收缩压的 Pearson 相关系数和系数为:0.003(ρ=0.00001,95%CI-0.229 至 0.224);BD 与 HR:-0.19(ρ=0.038,95%CI-0.399 至 0.038);BD 与 RR:-0.019(ρ=0.0004,95%CI-0.244 至 0.208)。乳酸水平异常升高的患者手术干预的可能性更大,OR 为 4.17(95%CI 1.57 至 11),但 BD 或任何生命体征均无此相关性,OR 分别为 2.53(95%CI 0.99 至 6.45)。

结论

分诊生命体征与穿透性创伤患者的乳酸或 BD 水平无相关性。乳酸水平异常升高的患者手术干预的可能性更大,但分诊生命体征或 BD 异常的患者并非如此。

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