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千伏锥形束计算机断层扫描成像中目标运动的影响。

The effects of target motion in kV-CBCT imaging.

作者信息

Padmanaban Sriram, Boopathy Raghavendiran, Kunjithapatham Bhuvana, Sukumar Prabakar, Nagarajan Vivekanandan

机构信息

Cancer Institution (WIA), Adyar Chennai Tamilnadu, India.

出版信息

Pol J Radiol. 2010 Jan;75(1):61-6.

Abstract

BACKGROUND

To study the impact of target motion in kV-CBCT imaging.

MATERIAL/METHODS: To simulate the respiratory movement, dynamic phantom was programmed to move in three-dimension with a period of four seconds and of two different amplitudes (PA1 and PA2). The targets of well defined geometries (cylinder, sphere, solid triangle, U-shaped and dumbbell) were made using wax. The static targets were CT imaged (reference image). Using CBCT, the targets in static and dynamic modes were imaged under full-fan beam. The line profiles along cranio-caudal direction, influence of target's initial moving phase and volume estimation using auto-contouring tool were used to analyze the effects of target motion on CBCT imaging.

RESULTS

Comparing the line profiles of targets in CBCT with CT, the length of average HU spread was reduced by 42.54±1.85%, except the cylindrical target which is by 19.35% for PA1. The percentage difference in reconstructed volume of static targets imaged using CBCT and CT (HU WW -500 to 0) ranges from -1.32% to -5.94%. The volume losses for targets imaged in dynamic mode PA1 ranges from 14.35% to 30.95% and for PA2 it was 21.29% to 43.80%. The solid triangle and cylindrical targets suffered the maximum and minimum volume losses respectively.

CONCLUSIONS

Non-gated CBCT imaging of the moving targets encounters significant loss of volumetric information, due to scatter artifacts. These may result in a systematic error in re-contouring when CBCT images are used for the re-planning work.

摘要

背景

研究千伏级锥形束计算机断层扫描(kV-CBCT)成像中目标运动的影响。

材料/方法:为模拟呼吸运动,对动态体模进行编程,使其以4秒为周期、两种不同幅度(PA1和PA2)进行三维运动。使用蜡制作具有明确几何形状(圆柱体、球体、实心三角形、U形和哑铃形)的目标。对静态目标进行CT成像(参考图像)。使用CBCT,在全扇束条件下对静态和动态模式下的目标进行成像。利用沿颅尾方向的线轮廓、目标初始运动相位的影响以及使用自动轮廓工具进行的体积估计,分析目标运动对CBCT成像的影响。

结果

将CBCT中目标的线轮廓与CT进行比较,平均HU扩展长度减少了42.54±1.85%,PA1条件下的圆柱形目标除外,其减少了19.35%。使用CBCT和CT成像(HU窗宽-500至0)的静态目标重建体积的百分比差异在-1.32%至-5.94%之间。动态模式PA1下成像目标的体积损失在14.35%至30.95%之间,PA2下为21.29%至43.80%。实心三角形和圆柱形目标分别遭受了最大和最小的体积损失。

结论

由于散射伪影,移动目标的非门控CBCT成像会遇到大量体积信息丢失。当将CBCT图像用于重新规划工作时,这些可能会导致重新轮廓描绘中的系统误差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c10/3389851/77706fc5eb36/poljradiol-75-1-61-g001.jpg

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