NHS Blood and Transplant, and Northern Deanery, Newcastle upon Tyne, Tyne and Wear, UK.
Transfusion. 2013 Mar;53(3):483-9. doi: 10.1111/j.1537-2995.2012.03782.x. Epub 2012 Jul 15.
An understanding of current and changing patterns of red blood cell (RBC) use will help predict future demands and aid future planning for transfusion services. It can also highlight areas where efforts to optimize RBC use are most likely to be productive.
Surveys were conducted in two 14-day periods of all RBC transfusions in a geographic region of England supplied by a single blood center. Data collection was prospective and used preprinted paper forms. Results were compared with two previous studies covering a period of 10 years.
The clinical fate of 8025 units of RBCs was recorded consistent with data on more than 99% of units issued and transfused during the survey period. The overall RBC transfusion rate has decreased from 45.5 to 36 units per 100,000 population from 1999 and 2009. Twenty-nine percent were used for surgical indications indicating a further decrease in surgical use compared to previous surveys. This decrease was limited solely to recipients of 50 to 80 years of age. Use for medical and obstetric/gynecologic indications has not changed significantly over 10 years.
Further decreases in surgical RBC use may be achievable but the aging population is likely to demand more blood for nonsurgical indications and efforts should be directed to optimizing use in these recipients. Comparative data on transfusion rates between regions or countries may be a useful tool for improving blood use.
了解当前和不断变化的红细胞 (RBC) 使用模式将有助于预测未来的需求，并为输血服务的未来规划提供帮助。它还可以突出最有可能优化 RBC 使用的努力的领域。
在英格兰一个由单个血液中心供应的地理区域内，进行了两次为期 14 天的所有 RBC 输血调查。数据收集是前瞻性的，使用预印纸质表格。结果与涵盖 10 年的两项先前研究进行了比较。
记录了 8025 个单位 RBC 的临床命运，与调查期间发出和输注的超过 99%的单位的数据一致。RBC 输血率从 1999 年和 2009 年的每 10 万人 45.5 单位降至 36 单位。29%用于手术指征，表明与以前的调查相比，手术使用率进一步下降。这种下降仅局限于 50 至 80 岁的受血者。10 年来，用于医疗和产科/妇科指征的 RBC 使用量没有明显变化。
进一步减少手术 RBC 使用量可能是可行的，但人口老龄化可能需要更多的血液用于非手术指征，应努力优化这些受血者的使用。区域或国家之间输血率的比较数据可能是改进血液使用的有用工具。
