Gambhir K K, Mathews J, Parui R, Cruz I A, Hosten A O, Dillard M G
Department of Medicine, Howard University Hospital, Washington, DC 20060.
J Natl Med Assoc. 1990 Oct;82(10):697-9.
We have studied the percentage of 22Na+ uptake in cell suspensions; 0.4 to 2.0 x 10(9) erythrocytes/mL from diabetic uremic patients with secondary hypertension and from normal subjects. Suspensions from diabetic uremic patients with secondary hypertension 0.42 +/- 0.06 to 2.05 +/- 0.28; normal subjects showed a percentage uptake of 22Na+ of 0.27 +/- 0.05 to 1.28 +/- 0.22. The uptake of 22Na+ in 2.0 x 10(9) cells/mL was 60% more (P less than .05) in diabetic uremic patients than in the controls. These studies indicate that 22Na+ influx determinations may be used to distinguish secondary hypertensive patients from normal subjects.
我们研究了细胞悬液中22Na+摄取的百分比；这些细胞悬液来自患有继发性高血压的糖尿病尿毒症患者和正常受试者，细胞浓度为0.4至2.0×10(9)个红细胞/毫升。患有继发性高血压的糖尿病尿毒症患者的细胞悬液中22Na+摄取百分比为0.42±0.06至2.05±0.28；正常受试者的22Na+摄取百分比为0.27±0.05至1.28±0.22。每毫升2.0×10(9)个细胞中，糖尿病尿毒症患者对22Na+的摄取比对照组多60%（P<0.05）。这些研究表明，22Na+流入量测定可用于区分继发性高血压患者和正常受试者。
