Müller O, Musoke P, Sen G, Moser R
League of Red Cross and Red Crescent Societies, Geneva, Switzerland.
J Trop Pediatr. 1990 Dec;36(6):283-6. doi: 10.1093/tropej/36.6.283.
Data of pediatric patients screened for HIV-1 infection between 1985 and 1989 were studied retrospectively in one of the major mission hospitals of Kampala (Uganda). Symptomatic HIV-1 infection was mainly acquired perinatally and was diagnosed in 87 per cent in children under 2 years of age. The mortality rate was 40 per cent in pediatric in-patients with symptomatic HIV-1 infection as compared to 12 per cent in overall pediatric inpatients. Symptoms included in the WHO clinical case definition for pediatric AIDS were mainly insensitive, unspecific and demonstrated a low positive predictive value. There was no difference in the prevalence of malaria and measles between HIV-1 positive and HIV-1 negative children.
1985年至1989年间，在坎帕拉（乌干达）的一家主要教会医院对筛查HIV-1感染的儿科患者数据进行了回顾性研究。有症状的HIV-1感染主要通过围产期获得，87%在2岁以下儿童中被诊断出来。有症状的HIV-1感染的儿科住院患者死亡率为40%，而儿科住院患者总体死亡率为12%。世卫组织儿科艾滋病临床病例定义中的症状主要不敏感、不具特异性，且阳性预测值较低。HIV-1阳性和HIV-1阴性儿童之间疟疾和麻疹的患病率没有差异。
