Schumacher Y O, Klodt F, Nonis D, Pottgiesser T, Alsayrafi M, Bourdon P C, Voss S C
Department of Sports Medicine, University of Freiburg, Freiburg, Germany.
Anti-Doping Laboratory, Doha, Qatar.
Int J Lab Hematol. 2012 Dec;34(6):641-7. doi: 10.1111/j.1751-553X.2012.01450.x. Epub 2012 Jul 16.
Dehydration, fluid shifts or changes in coagulation occurring during air travel can trigger distinct reactions in the haematological system. Athletes are concerned that these effects might impair sporting performance, increase the risk of thrombosis or cause abnormalities in blood values that might be mistaken for doping in the 'Athlete's biological passport' (ABP) a longitudinal monitoring of haematological variables in antidoping. The aim of the study was to investigate key variables of the ABP before and after a long-haul flight in athletes.
Fifteen endurance athletes were submitted to ABP blood samples in the morning before and after arrival of an 8 h flight. Two additional samples were obtained in the morning and the evening 3 days after the travel. Twelve nontravelling subjects served as controls.
Haemoglobin concentration was higher before than after travel in athletes (+0.5 g/dL, P = 0.038), a similar pattern was observed 3 days after the travel. No difference was observed in the control group. Reticulocyte% did not show any significant changes in neither of the groups.
The observed changes are in line with normal diurnal variations. There is no indication that travel will affect haematological variables in way that might be mistaken for blood doping.
航空旅行期间发生的脱水、体液转移或凝血变化可引发血液系统的不同反应。运动员担心这些影响可能会损害运动表现、增加血栓形成风险或导致血液值异常，而这些异常在反兴奋剂的“运动员生物护照”（ABP，一种对血液学变量进行纵向监测的反兴奋剂手段）中可能会被误认为是使用兴奋剂。本研究的目的是调查运动员长途飞行前后ABP的关键变量。
15名耐力运动员在8小时航班抵达前后的早晨接受ABP血样采集。旅行后3天的早晨和晚上又采集了两份样本。12名未旅行的受试者作为对照。
运动员旅行前的血红蛋白浓度高于旅行后（+0.5 g/dL，P = 0.038），旅行后3天观察到类似模式。对照组未观察到差异。两组的网织红细胞百分比均未显示任何显著变化。
观察到的变化与正常的昼夜变化一致。没有迹象表明旅行会以可能被误认为是血液兴奋剂的方式影响血液学变量。
