Department of Veterinary Public Health, Chulalongkorn University, Bangkok 10330, Thailand.
Arch Virol. 2012 Nov;157(11):2113-23. doi: 10.1007/s00705-012-1411-y. Epub 2012 Jul 18.
Highly pathogenic avian influenza (HPAI) virus subtype H5N1 was first reported in Myanmar in 2006. In this study, we have characterized 6 HPAI (H5N1) viruses recovered from 2007-2010 as well as three additional available nucleotide sequences representing Myanmar AI outbreaks. Phylogenetic analysis showed that the Myanmar viruses belong to HPAI (H5N1) clades 7, 2.3.2 and 2.3.4. The result suggested that the HPAI (H5N1) viruses recovered from Myanmar had been introduced into the country by multiple introductions. Genetic analysis of the viruses confirmed the HPAI characteristics of the viruses.
高致病性禽流感(HPAI)病毒亚型 H5N1 于 2006 年在缅甸首次报告。在本研究中,我们对 2007 年至 2010 年间从缅甸分离的 6 株 HPAI(H5N1)病毒以及另外 3 株代表缅甸 AI 暴发的可用核苷酸序列进行了特征描述。系统进化分析表明,缅甸病毒属于 HPAI(H5N1)7 、2.3.2 和 2.3.4 分支。结果表明,从缅甸分离的 HPAI(H5N1)病毒是由多次传入引入该国的。病毒的遗传分析证实了病毒的 HPAI 特征。