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Ribonucleoside 3'-phosphates as pro-moieties for an orally administered drug.

作者信息

Palte Michael J, Davis Amy K F, McGrath Nicholas A, Spiegel Carol A, Raines Ronald T

机构信息

Medical Scientist Training Program and Molecular & Cellular Pharmacology Graduate Training Program, University of Wisconsin-Madison, 750 Highland Avenue, Madison, WI 53705, USA.

出版信息

ChemMedChem. 2012 Aug;7(8):1361-4. doi: 10.1002/cmdc.201200243. Epub 2012 Jul 13.

DOI:10.1002/cmdc.201200243
PMID:22807330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3516917/
Abstract
摘要

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Int J Mol Sci. 2012;13(1):18-43. doi: 10.3390/ijms13010018. Epub 2011 Dec 22.
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Rational design and evaluation of mammalian ribonuclease cytotoxins.哺乳动物核糖核酸酶细胞毒素的合理设计与评估
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Microfabricated particulate drug-delivery systems.微制造颗粒药物输送系统。
Biotechnol J. 2011 Dec;6(12):1477-87. doi: 10.1002/biot.201100237. Epub 2011 Nov 11.
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A prodrug approach to improve the physico-chemical properties and decrease the genotoxicity of nitro compounds.前药策略改善硝基化合物的物理化学性质并降低遗传毒性。
Curr Pharm Des. 2011;17(32):3515-26. doi: 10.2174/138161211798194512.
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Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism.牛胰核糖核酸酶：首个酶促反应机制的五十年。
Biochemistry. 2011 Sep 20;50(37):7835-41. doi: 10.1021/bi201075b. Epub 2011 Aug 24.
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Applications of polymeric nanocapsules in field of drug delivery systems.聚合物纳米胶囊在药物递送系统领域的应用。
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Critical factors in the release of drugs from sustained release hydrophilic matrices.亲水凝胶骨架型药物控制释放系统中药物释放的关键因素
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