脆弱拟杆菌脑膜炎在先前使用甲砜霉素治疗失败后，甲硝唑治疗成功。
Bacteroides fragilis meningitis successfully treated with metronidazole after a previous failure with thiamphenicol.
作者信息
Soriano F, Aguado J M, Tornero J, Fernandez-Guerrero M L, Gómez-Garcés J L
出版信息
J Clin Microbiol. 1986 Sep;24(3):472-3. doi: 10.1128/jcm.24.3.472-473.1986.
Abstract
A case of pyogenic meningitis caused by Bacteroides fragilis in a 72-year-old woman is reported. Although the isolate was susceptible to thiamphenicol, the patient did not respond to this drug. Metronidazole, which showed high bactericidal activity, was administered and achieved sterilization of the cerebrospinal fluid and complete clinical response.
摘要
报告了一例72岁女性由脆弱拟杆菌引起的化脓性脑膜炎病例。尽管分离菌株对甲砜霉素敏感，但该患者对此药无反应。给予具有高杀菌活性的甲硝唑后，脑脊液实现了除菌，临床症状完全缓解。
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