活细胞超分辨率成像走向多色化。
Live-cell super-resolution imaging goes multicolor.
机构信息
Department of Biotechnology & Biophysics, Biozentrum, Julius-Maximilians-Universität Würzburg, Am Hubland, Würzburg, Germany.
出版信息
Chembiochem. 2012 Sep 3;13(13):1861-3. doi: 10.1002/cbic.201200347. Epub 2012 Jul 13.
PMID:22807353
Abstract
New resolutions: The combined use of photoactivatable fluorescent proteins and synthetic fluorophores considerably expands our options for multicolor super-resolution fluorescence imaging and enables for the first time the simultaneous imaging of more than two proteins with subdiffraction optical resolution in living cells.
摘要
新的决议
光活化荧光蛋白和合成荧光团的联合使用极大地扩展了我们进行多色超分辨率荧光成像的选择，并首次实现了在活细胞中以亚衍射光学分辨率同时对两种以上蛋白质进行成像。
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