Division of Public Health, University of Liverpool, Whelan Building, Quadrangle, Liverpool, L69 3GB, England.
Bull World Health Organ. 2012 Jul 1;90(7):522-31. doi: 10.2471/BLT.11.092643. Epub 2012 Apr 12.
To estimate how much more cardiovascular disease (CVD) mortality could be reduced in the United Kingdom through more progressive nutritional targets.
Potential reductions in CVD mortality in the United Kingdom between 2006 (baseline) and 2015 were estimated by synthesizing data on population, diet and mortality among adults aged 25 to 84 years. The effect of specific dietary changes on CVD mortality was obtained from recent meta-analyses. The potential reduction in CVD deaths was then estimated for two dietary policy scenarios: (i) modest improvements (simply assuming recent trends will continue until 2015) and (ii) more substantial but feasible reductions (already seen in several countries) in saturated fats, industrial trans fats and salt consumption, plus increased fruit and vegetable intake. A probabilistic sensitivity analysis was conducted. Results were stratified by age and sex.
The first scenario would result in approximately 12 500 fewer CVD deaths per year (range: 5500-30 300). Approximately 4800 fewer deaths from coronary heart disease and 1800 fewer deaths from stroke would occur among men, and 3500 and 2400 fewer, respectively, would occur among women. More substantial dietary improvements (no industrial trans fats, reduction in saturated fats and salt and substantial increases in fruit and vegetable intake) could result in approximately 30 000 fewer (range: 13 300-74 900) CVD deaths.
Excess dietary trans fats, saturated fats and salt, along with insufficient fruits and vegetables, generate a substantial burden of CVD in the United Kingdom. Further improvements resembling those attained by other countries are achievable through stricter dietary policies.
评估在英国通过更渐进的营养目标,可减少多少心血管疾病(CVD)死亡率。
通过综合 25 至 84 岁成年人的人口、饮食和死亡率数据,估计英国在 2006 年(基线)至 2015 年间 CVD 死亡率的潜在降低情况。从最近的荟萃分析中获得特定饮食变化对 CVD 死亡率的影响。然后,根据两种饮食政策情景,估算 CVD 死亡人数的潜在减少情况:(i)适度改善(简单假设最近的趋势将持续到 2015 年)和(ii)更实质性但可行的减少(在几个国家已经看到)饱和脂肪、工业反式脂肪和盐的消耗,以及增加水果和蔬菜的摄入量。进行了概率敏感性分析。结果按年龄和性别分层。
第一种情景每年可减少约 12500 例 CVD 死亡(范围:5500-30300)。男性冠心病死亡人数将减少约 4800 人,中风死亡人数将减少约 1800 人,女性冠心病死亡人数将减少约 3500 人,中风死亡人数将减少约 2400 人。更实质性的饮食改善(没有工业反式脂肪、减少饱和脂肪和盐以及大幅增加水果和蔬菜摄入量)可减少约 30000 例(范围:13300-74900)CVD 死亡。
过量的饮食反式脂肪、饱和脂肪和盐,以及不足的水果和蔬菜,给英国带来了大量的 CVD 负担。通过更严格的饮食政策,可以实现类似于其他国家所取得的进一步改善。