Pearson-Stuttard Jonathan, Bandosz Piotr, Rehm Colin D, Penalvo Jose, Whitsel Laurie, Gaziano Tom, Conrad Zach, Wilde Parke, Micha Renata, Lloyd-Williams Ffion, Capewell Simon, Mozaffarian Dariush, O'Flaherty Martin
Department of Public Health and Policy, University of Liverpool, Liverpool, United Kingdom.
School of Public Health, Imperial College London, London, United Kingdom.
PLoS Med. 2017 Jun 6;14(6):e1002311. doi: 10.1371/journal.pmed.1002311. eCollection 2017 Jun.
Large socio-economic disparities exist in US dietary habits and cardiovascular disease (CVD) mortality. While economic incentives have demonstrated success in improving dietary choices, the quantitative impact of different dietary policies on CVD disparities is not well established. We aimed to quantify and compare the potential effects on total CVD mortality and disparities of specific dietary policies to increase fruit and vegetable (F&V) consumption and reduce sugar-sweetened beverage (SSB) consumption in the US.
Using the US IMPACT Food Policy Model and probabilistic sensitivity analyses, we estimated and compared the reductions in CVD mortality and socio-economic disparities in the US population potentially achievable from 2015 to 2030 with specific dietary policy scenarios: (a) a national mass media campaign (MMC) aimed to increase consumption of F&Vs and reduce consumption of SSBs, (b) a national fiscal policy to tax SSBs to increase prices by 10%, (c) a national fiscal policy to subsidise F&Vs to reduce prices by 10%, and (d) a targeted policy to subsidise F&Vs to reduce prices by 30% among Supplemental Nutrition Assistance Program (SNAP) participants only. We also evaluated a combined policy approach, combining all of the above policies. Data sources included the Surveillance, Epidemiology, and End Results Program, National Vital Statistics System, National Health and Nutrition Examination Survey, and published meta-analyses. Among the individual policy scenarios, a national 10% F&V subsidy was projected to be most beneficial, potentially resulting in approximately 150,500 (95% uncertainty interval [UI] 141,400-158,500) CVD deaths prevented or postponed (DPPs) by 2030 in the US. This far exceeds the approximately 35,100 (95% UI 31,700-37,500) DPPs potentially attributable to a 30% F&V subsidy targeting SNAP participants, the approximately 25,800 (95% UI 24,300-28,500) DPPs for a 1-y MMC, or the approximately 31,000 (95% UI 26,800-35,300) DPPs for a 10% SSB tax. Neither the MMC nor the individual national economic policies would significantly reduce CVD socio-economic disparities. However, the SNAP-targeted intervention might potentially reduce CVD disparities between SNAP participants and SNAP-ineligible individuals, by approximately 8% (10 DPPs per 100,000 population). The combined policy approach might save more lives than any single policy studied (approximately 230,000 DPPs by 2030) while also significantly reducing disparities, by approximately 6% (7 DPPs per 100,000 population). Limitations include our effect estimates in the model; these estimates use interventional and prospective observational studies (not exclusively randomised controlled trials). They are thus imperfect and should be interpreted as the best available evidence. Another key limitation is that we considered only CVD outcomes; the policies we explored would undoubtedly have additional beneficial effects upon other diseases. Further, we did not model or compare the cost-effectiveness of each proposed policy.
Fiscal strategies targeting diet might substantially reduce CVD burdens. A national 10% F&V subsidy would save by far the most lives, while a 30% F&V subsidy targeting SNAP participants would most reduce socio-economic disparities. A combined policy would have the greatest overall impact on both mortality and socio-economic disparities.
美国的饮食习惯和心血管疾病(CVD)死亡率存在巨大的社会经济差异。虽然经济激励措施已证明在改善饮食选择方面取得成功,但不同饮食政策对CVD差异的量化影响尚未明确确立。我们旨在量化并比较特定饮食政策对美国总体CVD死亡率和差异的潜在影响,这些政策旨在增加水果和蔬菜(F&V)的消费并减少含糖饮料(SSB)的消费。
使用美国影响食品政策模型和概率敏感性分析方法,我们估计并比较了2015年至2030年期间美国人群中通过特定饮食政策情景可能实现的CVD死亡率降低和社会经济差异:(a)一项旨在增加F&V消费和减少SSB消费的全国性大众媒体宣传活动(MMC);(b)一项将SSB征税10%以提高价格的国家财政政策;(c)一项补贴F&V以降低价格10%的国家财政政策;(d)一项仅针对补充营养援助计划(SNAP)参与者补贴F&V以降低价格30%的针对性政策。我们还评估了一种综合政策方法,即结合上述所有政策。数据来源包括监测、流行病学和最终结果计划、国家生命统计系统、国家健康和营养检查调查以及已发表的荟萃分析。在各个政策情景中,预计全国10%的F&V补贴最为有益,到2030年可能在美国预防或推迟约150,500例(95%不确定区间[UI] 141,400 - 158,500)CVD死亡(DPPs)。这远远超过了仅针对SNAP参与者的30% F&V补贴可能导致的约35,100例(95% UI 31,700 - 37,500)DPPs、为期1年的MMC可能导致的约25,800例(95% UI 24,300 - 28,500)DPPs或10% SSB税可能导致的约31,000例(95% UI 26,800 - 35,300)DPPs。MMC和单独的国家经济政策都不会显著降低CVD社会经济差异。然而,针对SNAP的干预措施可能会使SNAP参与者和无资格参与SNAP的个体之间的CVD差异降低约8%(每10万人中减少10例DPPs)。综合政策方法可能比所研究的任何单一政策挽救更多生命(到2030年约230,000例DPPs),同时也显著降低差异,约6%(每10万人中减少7例DPPs)。局限性包括我们在模型中的效应估计;这些估计使用了干预性和前瞻性观察性研究(并非完全是随机对照试验)。因此它们并不完美,应被视为现有最佳证据。另一个关键局限性是我们仅考虑了CVD结果;我们所探讨的政策无疑会对其他疾病产生额外的有益影响。此外,我们没有对每个提议政策的成本效益进行建模或比较。
针对饮食的财政策略可能会大幅减轻CVD负担。全国10%的F&V补贴将挽救最多的生命;而针对SNAP参与者补贴30%的F&V将最大程度地减少社会经济差异。综合政策对死亡率和社会经济差异的总体影响最大。