Luo Jin-Dan, Wang Ping, Chen Jun, Liu Ben, Wang Shuo, Shen Bo-Hua, Xie Li-Ping
Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China.
Oncol Lett. 2012 Jul;4(1):71-74. doi: 10.3892/ol.2012.706. Epub 2012 May 4.
The aim of the study was to review the clinical features and treatments of 10 (9 males and 1 female; age range, 61-73 years; median age, 67 years) upper urinary tract inverted papilloma (IP) cases between 1995 and 2010. The clinical syndromes, diagnostic procedures, treatments and results of the follow-up were evaluated. The results showed that the site of tumor development was the ureter in 6 cases and the renal pelvis in 4 cases. It was also identified that 7 tumors developed on the left side and 3 developed on the right side of the ureter and renal pelvis, respectively. A nephroureterectomy was performed in the first 6 cases, while a partial ureterectomy was performed in 3 cases and a local resection was performed endoscopically in 1 case. All but 2 tumors were solitary, ranging from 5 to 30 mm in diameter. Occurrence in association with transitional cell carcinoma was identified in one case. All 10 patients were subject to follow-up (range, 19-120 months; median, 59 months), during which no recurrence was found. Local excision is considered as adequate treatment when upper urinary tract IP is diagnosed according to strictly defined criteria.
本研究旨在回顾1995年至2010年间10例上尿路内翻性乳头状瘤（IP）患者（9例男性，1例女性；年龄范围61 - 73岁，中位年龄67岁）的临床特征及治疗情况。对临床症状、诊断方法、治疗及随访结果进行了评估。结果显示，肿瘤发生部位为输尿管6例，肾盂4例。还发现输尿管及肾盂左侧发生肿瘤7例，右侧3例。前6例患者行肾输尿管切除术，3例行部分输尿管切除术，1例行内镜下局部切除术。除2例肿瘤外，其余均为单发，直径5至30毫米。1例患者同时合并移行细胞癌。10例患者均接受随访（范围19 - 120个月，中位时间59个月），随访期间均未发现复发。当根据严格定义的标准诊断上尿路IP时，局部切除被认为是充分的治疗方法。
