Annese V, Janssens J, Vantrappen G
Divisione di Gastroenterologia, Ospedale Generale C.S.S., San Giovanni Rotondo Foggia.
Minerva Dietol Gastroenterol. 1990 Jul-Sep;36(3):145-55.
Primary esophageal motility disorders consist of a complex group of motor disturbances, affecting the characteristics of esophageal contractions, occurrence of peristalsis and lower esophageal sphincter function. The medical treatment is still challenging because of the absence, except for Achalasia, of generally agreed criteria for diagnosis and the still unresolved relationship between esophageal symptoms and some motor abnormalities. In Achalasia, the medical therapy does not constitute a main role and should be reserved to selected conditions. Current medical therapies for Diffuse Esophageal Spasm and Esophageal Chest Pain are often considered less than satisfactory, however, a better physiopathological knowledge of these conditions might produce a more appropriate therapeutic management of the patients with continual and disabling symptoms.
原发性食管动力障碍由一组复杂的运动障碍组成，影响食管收缩的特征、蠕动的发生以及食管下括约肌功能。由于除贲门失弛缓症外，缺乏普遍认可的诊断标准，且食管症状与某些运动异常之间的关系仍未解决，因此药物治疗仍然具有挑战性。在贲门失弛缓症中，药物治疗并不起主要作用，应仅用于特定情况。目前针对弥漫性食管痉挛和食管胸痛的药物治疗通常被认为不尽人意，然而，对这些病症更好的生理病理学认识可能会为有持续且致残症状的患者带来更合适的治疗管理。
