[出生后分化过程中感觉运动皮层神经元染色质的结构与转录活性]
[The structure and transcription activity of the neuronal chromatin in the sensorimotor cortex during postnatal differentiation].
作者信息
Grigor'eva A V, Bul'chuk O V, Iushchenko O M, Iarygin V N
出版信息
Ontogenez. 1990 Sep-Oct;21(5):517-23.
PMID:2280970
Abstract
We report findings about age-related changes in the chromatin structure detected using ammoniacal silver and changes in the transcription rate in neurons by layers II-V of the sensomotor cortex of rats at days 7, 14 and 60 of postnatal life. Different types of neurons showed different average template activity but similar patterns of its age-related changes. The rearrangement of the chromatin structure in various types of cortical cells showed different orientation after day 14 of postnatal life.
摘要
我们报告了关于使用氨银检测到的染色质结构与年龄相关变化的研究结果，以及出生后第7天、14天和60天大鼠感觉运动皮层II-V层神经元转录率的变化。不同类型的神经元显示出不同的平均模板活性，但其与年龄相关的变化模式相似。出生后第14天之后，各种类型皮质细胞中染色质结构的重排呈现出不同的方向。
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