Singh Ajai R, Singh Shakuntala A
Mens Sana Monogr. 2004 Jan;2(1):45-51.
Most clinicians and researchers are concerned with recent advances in psychiatry. This involves the danger whether something time-tested may get sidelined for extra-scientific reasons. That the pharmaceutical industry and superspecialist researcher may keep churning out new findings to impress audiences is only a partial truth. Research progresses by refutation and self-correction. Acceptance in science is always provisional; changing paradigms, frameworks of enquiry and raising new questions is integral to break through in scientific knowledge. Hence, there is in science a constant concern with the new. Moreover, the number of treatment non- responders to the time-tested swells with time, and researchers feel challenged to find ways and means of resolving their difficulties. Newer challenges need newer strategies. Obsession with the most recent can lead us astray, but a healthy evidence-based acceptance of the new is essential for advancement in psychiatric research. As indeed of research in all fields of medicine. And of science in general. The role of lithium and newer mood stabilizers in bipolar disorders are taken as examples to highlight this point.
大多数临床医生和研究人员关注的是精神病学的最新进展。这涉及到一个风险，即一些经过时间考验的东西可能会因为非科学原因而被边缘化。制药行业和超级专家型研究人员可能会不断推出新发现以给受众留下深刻印象，这只是部分事实。研究是通过反驳和自我修正来推进的。科学中的接受总是暂时的；改变范式、探究框架并提出新问题是科学知识突破的不可或缺部分。因此，科学中一直关注新事物。此外，随着时间的推移，对经过时间考验的治疗方法无反应的患者数量不断增加，研究人员感到有挑战去寻找解决他们困难的方法和手段。新的挑战需要新的策略。对最新事物的痴迷可能会使我们误入歧途，但基于证据对新事物的健康接受对于精神病学研究的进展至关重要。医学所有领域的研究以及一般科学领域的研究确实都是如此。以锂和新型情绪稳定剂在双相情感障碍中的作用为例来强调这一点。
