National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA.
J Occup Environ Hyg. 2012;9(9):543-55. doi: 10.1080/15459624.2012.699388.
In early 2006, the National Institute for Occupational Safety and Health created a field research team whose mission is to visit a variety of facilities engaged in the production, handling, or use of engineered nanomaterials (ENMs) and to conduct initial emission and exposure assessments to identify candidate sites for further study. To conduct the assessments, the team developed the Nanoparticle Emission Assessment Technique (NEAT), which has been used at numerous facilities to sample multiple engineered nanomaterials. Data collected at four facilities, which volunteered to serve as test sites, indicate that specific tasks can release ENMs to the workplace atmosphere and that traditional controls such as ventilation can be used to limit exposure. Metrics such as particle number concentration (adjusted for background), airborne mass concentration, and qualitative transmission electron microscopy were used to determine the presence, nature, and magnitude of emissions and whether engineered nanomaterials migrated to the workers' breathing zone. [Supplementary materials are available for this article. Go to the publisher's online edition of Journal of Occupational and Environmental Hygiene for the following free supplemental resource: a PDF file containing information on facilities, a description of processes/tasks, existing controls, and sampling strategy, and a PDF file containing TEM images according to facility and task.].
2006 年初,美国国家职业安全与健康研究所创建了一个实地研究小组,其任务是访问从事工程纳米材料(ENMs)生产、处理或使用的各种设施,并进行初步的排放和暴露评估,以确定进一步研究的候选地点。为了进行评估,该小组开发了纳米颗粒排放评估技术(NEAT),该技术已在许多设施中用于对多种工程纳米材料进行采样。在自愿作为测试点的四个设施中收集的数据表明,特定的任务可以将 ENMs 释放到工作场所的大气中,并且可以使用传统的控制措施(如通风)来限制暴露。使用颗粒数浓度(背景调整)、空气中的质量浓度和定性透射电子显微镜等指标来确定排放物的存在、性质和程度,以及工程纳米材料是否迁移到工人的呼吸区。[本文提供了补充材料。请访问《职业与环境卫生杂志》的出版商在线版本,以获取以下免费补充资源:一个包含设施信息、工艺/任务描述、现有控制措施和采样策略的 PDF 文件,以及一个根据设施和任务包含 TEM 图像的 PDF 文件。]